持续短阵快速脉冲刺激对情绪加工脑网络影响的研究

发布时间：2018-03-12 07:17

  本文选题：事件相关谱扰动　切入点：持续短阵快速脉冲刺激　出处：《生物医学工程学杂志》2017年04期 　论文类型：期刊论文

【摘要】：本文旨在研究持续短阵快速脉冲刺激(c TBS)干预对情绪加工脑功能网络的影响。我们采用c TBS技术对10名受试者的左前额背外侧皮质(DLPFC)区域进行干预,同时记录干预前后受试者进行情绪面孔性别识别任务时的头皮脑电(EEG)信号,然后采用EEG信号相位同步值来衡量两个脑网络节点间的连接强度,并运用网络效率来描述脑区的信息传递效率。研究结果发现,经由c TBS技术干预受试者脑区,再采用情绪面孔图片刺激后,100~300 ms时间窗内的EEG信号的β频段的事件相关功率明显增强;不同的情绪图片刺激下,中性和负性情绪图片刺激的EEG信号全局相位同步值比正性情绪刺激下更高;情绪加工脑网络小世界特性增强。综上所述,本文通过研究左侧DLPFC活跃性改变对情绪加工脑网络的影响,初步探索了情绪加工脑网络机制,为以后的情绪加工脑网络研究提供了参考。
[Abstract]:The purpose of this study was to investigate the effects of continuous short array rapid pulse stimulation on the functional network of emotional processing brain. We used c TBS technique to intervene in the DLPFC region of the left dorsolateral frontal cortex in 10 subjects. At the same time, the scalp electroencephalogram (EGG) signals were recorded before and after the intervention, and the EEG signal phase synchronization value was used to measure the connection strength between the two brain network nodes. The network efficiency was used to describe the efficiency of information transmission in the brain region. The results showed that the c TBS technique was used to interfere with the brain region of the subjects. After stimulation with emotional face image, the incident correlation power of 尾 band of EEG signal in 100 Ms time window was significantly increased, while under different emotional picture stimulation, The global phase synchronization value of EEG signal of neutral and negative emotional picture stimulation is higher than that of positive emotional stimulation, and the small world characteristics of emotional processing brain network are enhanced. By studying the effect of the change of left DLPFC activity on emotional processing brain network, this paper preliminarily explored the mechanism of emotional processing brain network, which provided a reference for the future research of emotional processing brain network.
【作者单位】： 上海大学通信与信息工程学院;上海大学钱伟长学院;上海交通大学医学院附属精神卫生中心脑电影像室;
【基金】：国家自然科学基金(61171032,61571283) 上海市教委自然科学创新重点项目(12ZZ099)
【分类号】：R338;TN911.7
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本文编号：1600540