上海先进质子治疗装置旋转机架优化设计

发布时间：2018-03-27 20:17

本文选题：质子治疗装置　切入点：旋转机架　出处：《中国科学院研究生院（上海应用物理研究所）》2015年博士论文

【摘要】：质子治疗装置是国际上新型治愈肿瘤的大型医疗设备，其中的旋转机架（Gantry）具有结构大、精度高的特点。上海质子治疗示范装置是国内首次对质子治疗技术的全面自主研发，其中新型的旋转机架是具有180度回转角度，旋转半径5.4m，重达162t的大型精密机械结构。作为首台国内自主研发的旋转机架，其瞄准目前国际上正在积极研发的新型半回转的结构，设计主体结构与指标参数与国际接轨，具有空间大、重量轻、性价比高等特点。但由于参考资料匮乏、等中心精度要求极高、配套建筑设计复杂，同时又必须具备高性价比以适应市场竞争，所以其设计难度极高。本文先介绍了质子治疗技术的概况，然后较系统的介绍了目前国际上旋转机架的发展以及试研时期的一些计算与分析。本文的目的：为保证旋转机架的结构具有高性价比，必须在保证精度的情况下进行结构优化以大幅减轻整体重量，从而达到质优价廉。采用的方法：采用物理优化、经验设计优化、拓扑优化与尺寸优化的多种方法综合运用。运用的主要结构优化设计的理论基础：拓扑优化ESO有限元法，尺寸优化中的遗传算法与序列二次规划算法以及试验设计方法与响应面技术。运用的软件与计算过程：综合采用Solidworks、ANSYS、Optimus软件分别进行主要零件结构的拓扑与尺寸优化，文章重点阐述其主要优化过程并对结构进行验算。优化的结果：通过对多个主要部件的优化设计和计算使得优化后的旋转机架重量从240t降至162t，仍然能达到等中心精度要求。这是结构优化设计方法首次在旋转机架设计的应用，起到了非常好的效果，也将结果运用到后续的实际生产制造过程中，，是非常具有意义的研究工作。
[Abstract]:The proton therapy device is a new type of large medical equipment for curing tumors in the world. Among them, the rotating frame Gantrye has the characteristics of large structure and high precision. The Shanghai proton therapy demonstration device is the first fully independent development of proton therapy technology in China. Among them, a new type of rotary frame is a large precision mechanical structure with an angle of 180 degrees of rotation, a rotating radius of 5.4 m and a weight of 162 tons. As the first self-developed rotating frame in China, it aims at a new type of semi-rotating structure, which is currently being actively developed in the world. The structure and index parameters of the design body are in line with the international standard, and have the characteristics of large space, light weight, high performance-to-price ratio, etc. However, due to the lack of reference materials, the precision of the isocentric structure is very high, and the design of supporting buildings is complex. At the same time, it must have high performance and price ratio to adapt to market competition, so it is very difficult to design. This paper first introduces the general situation of proton therapy technology, and then systematically introduces the development of rotating frame in the world and some calculation and analysis in the period of trial and research. The purpose of this paper: in order to ensure that the structure of the rotating frame has high performance-price ratio, it is necessary to optimize the structure under the condition of ensuring precision in order to greatly reduce the overall weight and achieve the high quality and low price. Methods adopted: physical optimization, empirical design optimization, topology optimization and dimension optimization. The main theoretical basis of structural optimization design are topology optimization ESO finite element method, genetic algorithm and sequential quadratic programming algorithm in dimension optimization, experimental design method and response surface technology. The application of software and calculation process: SolidworksAnsys Optimus software is used to optimize the topology and size of the main parts respectively. The main optimization process and checking calculation of the structure are described in this paper. The result of optimization: through the optimization design and calculation of several main components, the weight of the optimized rotating rack can be reduced from 240 t to 162 t, and the accuracy of the rotation frame can still be achieved. This is the first application of the structural optimization design method in the design of the rotating rack. It has a very good effect, and it is a very meaningful research work to apply the results to the subsequent actual manufacturing process.
【学位授予单位】：中国科学院研究生院（上海应用物理研究所）
【学位级别】：博士
【学位授予年份】：2015
【分类号】：TH774

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