三维锥形束CT和二维Exactrac影像引导放疗系统的研究

发布时间：2019-01-15 23:36

【摘要】：影像引导放疗(IGRT)为精确放疗的先决条件,正在逐渐被越来越多的医院采用,在不远的将来会成为一种重要的放射治疗辅助模式。本文主要介绍了现今放疗界一些主流的影像引导放疗设备和他们未来的发展。Novalis TX系统是由美国瓦里安公司(Varian)和德国博医来公司(Brainlab AG)合作生产的一款先进医用加速器,包括了多种形式的影像引导放疗(IGRT)设备:机载影像仪(OBI,On-Board Imager),,Exactrac系统,以及电子射野影像验证系统(EPID)。这三种影像引导设备各自具备不同的成像原理,性能不同。笔者在本文重点专注在Novalis TX医用加速器上的三维锥形束(CBCT)影像引导系统,和二维(Exactrac)影像引导系统。研究了他们的机器性能,成像原理。最后通过模体实验,具体对比了这两种影像引导设备针对人体不同部位上的定位精度,并通过分析实验结果。然后,又选择了8位头部肿瘤病人进行了临床研究。发现两种影像引导设备最后得出的摆位误差结果相近,但是在人体不同部位上,又略有差别。具体表现在头部肿瘤时,Exactrac系统精度稍高,而对体部和盆腔病人进行摆位时,锥形束CT影像引导设备能够提供的图像质量较高,摆位较为精确。
[Abstract]:Imaging guided radiotherapy (IGRT), as a prerequisite for accurate radiotherapy, is being gradually adopted by more and more hospitals and will become an important assistant mode of radiotherapy in the near future. This paper mainly introduces some mainstream image-guided radiotherapy equipment and their future development in the field of radiotherapy. The. Novalis TX system is an advanced medical accelerator produced by (Varian) of the United States of America and (Brainlab AG) of Germany. It includes a variety of imaging guided radiotherapy (IGRT) equipment: airborne imaging instrument (OBI,On-Board Imager), Exactrac system) and electronic field image verification system (EPID). These three kinds of image guiding devices have different imaging principles and different performance. In this paper, the author focuses on the three-dimensional conical beam (CBCT) image guidance system and the two-dimensional (Exactrac) image guidance system on the Novalis TX medical accelerator. Their mechanical properties and imaging principles were studied. Finally, the positioning accuracy of the two kinds of image guiding devices for different parts of human body is compared through the motif experiment, and the experimental results are analyzed. Then, 8 patients with head tumor were selected for clinical study. It is found that the results of the two kinds of imaging guiding devices are similar in the end, but slightly different in different parts of human body. In the case of head tumors, the accuracy of the Exactrac system is slightly higher, but when the body and pelvic patients are placed, the conical beam CT imaging guidance equipment can provide higher image quality and more accurate positioning.
【学位授予单位】：清华大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：TH789

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