面向脑状态监测的脑电与脑氧信号采集系统

发布时间：2018-01-12 23:27

本文关键词：面向脑状态监测的脑电与脑氧信号采集系统　出处：《浙江大学》2017年硕士论文　论文类型：学位论文

【摘要】：大脑是人体最重要的部位,几乎人体所有的活动都与大脑有密切相关的联系。对大脑健康状态的检测一直是人们研究的重点,现如今有许多检测技术可应用于大脑相关疾病的检测。其中脑电图(EEG)和近红外光谱技术(NIRS)具有良好的时间分辨率,已经被广泛的应用于大脑健康状态监护领域。脑电是由大脑神经活动的电信号产生的,可以反映大脑神经活动和相关代谢信息,而近红外光谱技术(NIRS)可以检测组织的血液相关参数,可以对大脑的血液活动或代谢状态进行有效评估。采用两种检测技术共同对大脑健康状态信息进行检测,将脑电图与血液相关参数所包含的信息相结合,可以完成对大脑健康更加全面的监护。本文基于脑电图和近红外光谱检测技术,完成脑电和脑氧信号采集系统的初步研发,采用双通道脑电和单通道脑氧信号的采集的方案,检测的部位主要是人脑前额脑区部位。本文首先介绍了大脑状态检测技术的研究现状和发展,特别是近年来出现的多种脑状态检测技术相结合的研究。然后介绍了脑电信号检测技术和近红外光谱技术的基本原理,并对系统的采集方案和校准原理加以说明。脑电信号采集模块是基于TI公司的ADS1299进行设计的,在ADS1299前端加入滤波电路和保护电路等预处理电路以保证电路的安全。脑氧信号采集模块采用双波长、双光电探测器的设计方案,采用LED发光二极管作为光源,采用微处理器STM32对脑氧信号进行采样并控制LED驱动电路调节电流大小。本文对系统进行了性能测试和系统参数的测量,采用标准脑电信号作为信号源对脑电采集系统的性能进行了验证,采用积分球原理对脑氧采集系统进行了校准实验,并对人体进行实际测量实验。系统的实验结果达到了较好的效果,初步确定此系统的可靠性和实用性。
[Abstract]:The brain is the most important part of the human body, almost all human activities are closely related to the brain. The detection of brain health status has been the focus of research. Nowadays, many detection techniques can be used in the detection of brain related diseases. Among them, electroencephalogram (EEG) and near infrared spectroscopy (NIR) have good time resolution. It has been widely used in the field of brain health monitoring. EEG is generated by electrical signals of brain nerve activity, which can reflect the brain nerve activity and related metabolic information. Near infrared spectroscopy (NIR) can be used to detect the blood parameters of tissues. It can effectively evaluate the blood activity or metabolic state of the brain. Two kinds of detection techniques are used to detect the information of the brain health state together, and the EEG is combined with the information contained in the blood related parameters. This paper based on EEG and near infrared spectrum detection technology to complete EEG and EEG and EEG signal acquisition system preliminary development. This paper introduces the research status and development of brain state detection technology, which is mainly located in the prefrontal region of human brain by the method of two channel EEG and single channel cerebral oxygen signal acquisition. Especially in recent years a variety of brain state detection technology combined research. Then the basic principles of EEG detection technology and near-infrared spectroscopy technology are introduced. The acquisition scheme and calibration principle of the system are explained. The EEG acquisition module is designed based on TI's ADS1299. Pre-processing circuits such as filter circuit and protection circuit are added to the front end of ADS1299 to ensure the safety of the circuit. The design of dual-wavelength and dual-photodetector is used in the module of cerebral oxygen signal acquisition. The LED light-emitting diode is used as the light source. The microprocessor STM32 is used to sample the cerebral oxygen signal and to control the current size of the LED drive circuit. The performance of the system and the measurement of the system parameters are tested in this paper. The performance of the EEG acquisition system is verified by using the standard EEG signal as the signal source, and the calibration experiment of the EEG acquisition system is carried out by using the integral sphere principle. The experimental results of the system are satisfactory, and the reliability and practicability of the system are preliminarily determined.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：TP274.2;R318

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