CT值直方图鉴别诊断骨巨细胞瘤与动脉瘤样骨囊肿的效能

发布时间：2017-12-31 09:46

本文关键词：CT值直方图鉴别诊断骨巨细胞瘤与动脉瘤样骨囊肿的效能　出处：《中国医学影像技术》2017年01期 　论文类型：期刊论文

【摘要】：目的探讨CT值直方图在骨巨细胞瘤(GCT)与动脉瘤样骨囊肿(ABC)中的鉴别诊断价值。方法收集接受CT扫描且经病理证实的骨GCT患者34例和ABC患者9例,在病灶最大层面选取ROI,获取CT值直方图,并记录平均CT值、峰值CT值、偏度值及峰度值,采用两独立样本t检验分析GCT和ABC各参数的差异,并对有统计学差异的指标采用ROC确定最佳诊断阈值,并计算曲线下面积、敏感度、特异度和准确率。结果GCT平均CT值和峰值CT值均显著高于ABC(t=-5.62,-5.81,P均0.05),ABC偏度值和峰度值大于GCT,但差异无统计学意义(t=1.58,0.75,P均0.05)。诊断GCT的平均CT值和峰值CT值的ROC曲线下面积分别为0.96和0.95(P均0.01),最佳诊断阈值分别为36.67 HU和36.85 HU,此时其敏感度、特异度、准确率分别为94.12%(32/34),88.89%(8/9)、93.02%(40/43)和97.06%(33/34)、88.89%(8/9)、95.35%(41/43)。结论 CT值直方图对GCT和ABC的鉴别诊断具有较高的临床应用价值,平均CT值和峰值CT值在两者的鉴别诊断中均具有较高的诊断准确率。
[Abstract]:Objective to investigate the role of CT value histogram in giant cell tumor of bone (GCTs) and aneurysm like bone cyst (ABC). Methods 34 cases of bone GCT and 9 cases of ABC were collected. ROI was selected at the maximum level of the lesion, and the histogram of CT value was obtained, and the average CT value, the peak CT value, the deviation value and the kurtosis value were recorded. T test of two independent samples was used to analyze the difference of parameters between GCT and ABC. ROC was used to determine the best diagnostic threshold and the area under the curve and sensitivity were calculated. Results the average CT value and the peak CT value of GCT were significantly higher than those of ABCs (P < 0.05). The deviation and kurtosis of ABC were higher than that of GCT, but the difference was not statistically significant. The area under the ROC curve of the average CT value and the peak CT value of GCT were 0.96 and 0.95 respectively (P < 0.01). The optimal diagnostic thresholds were 36.67 Hu and 36.85 HU.Its sensitivity, specificity and accuracy were 94.12 / 32 / 34 and 88.89 / 8 / 9, respectively. 93.02 / 40 / 43) and 97.06 / 33 / 34 / 88.89 / 8 / 9). 95.35% 41 / 430.Conclusion CT value histogram has high clinical value in differential diagnosis of GCT and ABC. Both the mean CT value and the peak CT value have high diagnostic accuracy.
【作者单位】：长江大学附属第一医院放射科;中国医科大学附属第一医院放射科;
【分类号】：R738;R681;R730.44
【正文快照】： 骨巨细胞瘤(giant cell tumor of bone,GCT)是临床较常见的良性骨肿瘤,但具有潜在恶性,约5%~10%病变呈侵袭性生长,甚至可发生肺转移[1-2]。动脉瘤样骨囊肿(aneurysmal bone cyst,ABC)是一种良性骨肿瘤样病变,以20岁以下青少年多见。两者均表现为膨胀性、溶骨性骨质破坏,尽管影

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