MDCT对肾透明细胞癌Fuhrman分级诊断价值的研究
发布时间:2018-01-02 01:33
本文关键词:MDCT对肾透明细胞癌Fuhrman分级诊断价值的研究 出处:《中国临床医学影像杂志》2017年07期 论文类型:期刊论文
【摘要】:目的:探讨肾透明细胞癌(cc RCC)MDCT影像学表现与Fuhrman分级之间的关系。方法:回顾性分析113例经手术病理证实的cc RCC的MDCT影像资料。两名放射科医生双盲记录患者的影像学特征,包括肿瘤大小、囊性或实性、钙化、不均匀性、坏死比、生长方式等,并与Fuhrman分级结果进行统计学分析。结果:14/15例囊性cc RCC为低级别(FuhrmanⅠ~Ⅱ级);在相对较多的实性cc RCC中,20/27例浸润型cc RCC为高级别(FuhrmanⅢ~Ⅳ级)。单因素分析显示肿瘤越大(临界值为4 cm),Fuhrman分级越高(χ~2=11.441,P0.001);高级别以实性为主cc RCC中钙化和坏死比≥0.6较低级别实性cc RCC多见(χ~2=29.007,P0.001;χ~2=18.454,P=0.030)。多因素分析提示肿瘤大小、浸润性生长、坏死比≥0.6是实性为主cc RCC FuhrmanⅢ~Ⅳ级的独立预测因素(OR:0.122,P=0.002;OR:13.234,P=0.002;OR:12.891,P=0.031)。结论:MDCT对预测cc RCC Fuhrman分级有较大的应用价值。囊性cc RCC倾向于低级别。以实性为主cc RCC中,肿瘤越大、浸润性生长、坏死比(≥0.6)越高,均预示较高的Fuhrman分级。
[Abstract]:Objective: to study the RCC in renal clear cell carcinoma (RCC). The relationship between MDCT imaging findings and Fuhrman grading. Methods: a retrospective analysis of 113 cases of cc proved by surgery and pathology. MDCT data of RCC. Imaging features of two radiologists were recorded in double blind. These include tumor size, cystic or solid, calcification, heterogeneity, necrosis ratio, growth pattern, etc. Results 15 / 14 / 15 cases of cystic cc RCC were of low grade Fuhrman 鈪,
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