脓毒症患者血清氨基酸末端B型利钠肽前体和心肌酶水平及临床意义

发布时间：2018-01-03 12:38

  本文关键词：脓毒症患者血清氨基酸末端B型利钠肽前体和心肌酶水平及临床意义　出处：《中国老年学杂志》2017年01期 　论文类型：期刊论文

  更多相关文章： 脓毒症 血清氨基酸末端B型利钠肽前体(NT-pro BNP) 心肌酶

【摘要】：目的检测脓毒症患者血清中氨基酸末端B型利钠肽前体(NT-pro BNP)和心肌酶的水平,分析其临床意义。方法脓毒症患者72例作为观察组,同期体检未见明显器质性疾病的成人25例血清标本作为对照组。检测两组中NT-pro BNP、谷草转氨酶(AST)、乳酸脱氢酶(LDH)、磷酸肌酸激酶(CK)、磷酸肌酸激酶同工酶(CK-MB)的水平。结果观察组血清中NT-pro BNP、AST、LDH、CK、CK-MB的水平均明显高于对照组。观察组中NT-pro BNP、AST、LDH、CK、CK-MB的水平与患者的预后密切相关,相关分析显示急性生理与慢性健康(APACHE)Ⅱ评分均与NT-pro BNP、AST、LDH、CK、CK-MB的水平呈正相关性。结论脓毒症患者NT-pro BNP和心肌酶各指标的表达均升高,其不仅促进病变的进展,还对判断病变的严重程度及预后有一定价值。
[Abstract]:Objective to detect the levels of NT-pro BNPs and myocardial enzymes in serum of sepsis patients. Methods 72 patients with sepsis were treated as observation group. At the same time, the serum samples of 25 adults with no obvious organic diseases were used as control group. NT-pro, aspartate aminotransferase and lactate dehydrogenase were detected in the two groups. Results the serum levels of creatine phosphokinase (CK) and creatine phosphokinase isoenzyme (CK-MBB) were measured. The levels of CK-MB were significantly higher than those of the control group. The level of CK-MB in the NT-pro BNPN ASTN was closely related to the prognosis of the patients. Correlation analysis showed that both acute physiological and chronic health Apache 鈪，

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