血必净注射液治疗脓毒性休克的临床价值

发布时间：2018-01-07 19:36

本文关键词：血必净注射液治疗脓毒性休克的临床价值　出处：《中国现代药物应用》2017年05期 　论文类型：期刊论文

【摘要】：目的探讨采用血必净注射液治疗对脓毒性休克的临床价值。方法 88例脓毒性休克患者,采用随机分组法将其分为对照组和研究组,各44例。对照组给予液体复苏、血管活性药物、抗生素等常规综合治疗措施,研究组在对照组治疗基础上同时给予血必净注射液治疗。治疗1周后观察两组的治疗效果。结果经过1周治疗后,研究组总有效率为90.91%,高于对照组的72.73%,差异具有统计学意义(P0.05)。治疗期间研究组有7例(15.91%)患者发生多器官功能障碍综合征(MODS),对照组有19例(43.18%)发生MODS,研究组患者MODS发生率低于对照组,差异有统计学意义(P0.05)。结论对脓毒性休克患者使用血必净注射液治疗可以阻滞病情进展,对炎性因子、毒素、细菌均有强效抑制作用,降低死亡率。
[Abstract]:Objective to explore the clinical value of Xuebijing injection in the treatment of septic shock. Methods 88 patients with septic shock were randomly divided into control group and study group. The control group was treated with conventional comprehensive therapy such as fluid resuscitation, vasoactive drugs and antibiotics. The study group was treated with Xuebijing injection at the same time on the basis of the treatment in the control group. After one week of treatment, the therapeutic effect of the two groups was observed. Results after one week of treatment, the total effective rate of the study group was 90.91%. The difference was statistically significant (P 0.05). During the treatment period, there were 7 patients with multiple organ dysfunction syndrome (MODS) in the study group. There were 19 cases of mods in the control group, and the incidence of MODS in the study group was lower than that in the control group. Conclusion Xuebijing injection can block the progress of the disease, and has strong inhibitory effect on inflammatory factors, toxins and bacteria in septic shock patients. Reduce mortality.
【作者单位】：阳江市人民医院重症监护一区;
【分类号】：R459.7
【正文快照】： 脓毒性休克是一组主要因革兰阴性菌引起的组织灌注不足、全身炎性反应症状,好发于免疫力低下或有慢性疾病患者,如恶性肿瘤、胆道感染、糖尿病、胃肠道感染等患者。脓毒性休克的病情危重,容易引起多器官功能衰竭(MOF)、急性呼吸窘迫综合征(ARDS)等并发症[1-5]。据临床不完全统

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