347例SARI病例15种常见呼吸道病原特征分析

发布时间：2018-01-09 14:29

本文关键词：347例SARI病例15种常见呼吸道病原特征分析　出处：《病毒学报》2017年05期 　论文类型：期刊论文

【摘要】：了解新疆维吾尔自治区人民医院住院严重急性呼吸道感染(Severe acute respiratory infection,SARI)病例呼吸道病原的构成及主要病原的流行规律,为SARI的防控提供线索和依据。应用多重PCR方法对2015年8月至2016年7月期间在新疆维吾尔自治区人民医院儿科、呼吸科、急诊科住院,且符合SARI病例定义的每周二、周四、周六新入院的患者进行检测。347份标本中检出14种呼吸道病原,未检测出衣原体,检出病毒阳性标本144份,阳性率为41.50%,检出前4位的病毒依次是,流感病毒72份、鼻病毒18份、呼吸道合胞病毒15份、偏肺病毒和副流感病毒各13份,阳性率分别为为20.75%,5.19%,4.32%,3.75%,3.75%,检出细菌阳性标本数为155份,阳性率为44.67%,其中肺炎链球菌阳性108份、流感嗜血杆菌阳性62份,肺炎支原体阳性13份,阳性率分别为31.12%、17.87%、3.75%;在108份肺炎链球菌阳性标本中41份标本合并病毒感染。新疆维吾尔自治区人民医院SARI病例病原主要以流感病毒,肺炎链球菌和流感嗜血杆菌为主,各年龄组均有检出,检出病原阳性高峰为冬春季;5岁及以下标本中检出腺病毒和百日咳杆菌会增加收住ICU的风险。
[Abstract]:Severe acute respiratory infection in the Xinjiang Uygur Autonomous Region people's Hospital (Severe acute respiratory infection, about SARI) epidemic cases of respiratory pathogens and pathogens, and provide a basis for SARI prevention and control. The application of multiplex PCR method for the period from August 2015 to July 2016 in the pediatric department of respiration, the Xinjiang Uygur Autonomous Region people's Hospital, emergency department of the hospital, and in accordance with the case definition of SARI every Tuesday, Thursday, Saturday 14 respiratory pathogen detection new hospitalized patients were detected.347 specimens, did not detect Chlamydia detection, virus positive samples were 144, the positive rate was 41.50%, were the top 4 viruses were influenza virus, 72 copies, 18 copies of rhinovirus, respiratory syncytial virus 15 a partial lung virus and parainfluenza virus 13, the positive rate was 20.75%, 5.19%, 4.32%, 3.75%, 3.75%, the number of bacteria were positive 155, the positive rate was 44.67%, of which 108 samples were positive for Streptococcus pneumoniae, Haemophilus influenzae positive 62, Mycoplasma positive 13, positive rates were 31.12%, 17.87%, 3.75%; in 108 samples of Streptococcus pneumoniae was detected in 41 specimens with virus infection. The main pathogen of the Xinjiang Uygur Autonomous Region people's Hospital of SARI cases with influenza virus, Streptococcus pneumoniae and Haemophilus influenzae, were detected in each age group, pathogenic positive peak for the winter and spring; were under the age of 5 and the detection of adenovirus and Bordetella pertussis will increase the risk of admission to the ICU.

【作者单位】：新疆维吾尔自治区疾病预防控制中心;
【基金】：2014年乌鲁木齐市科技计划(项目号:Y141310038),题目:乌鲁木齐市严重急性下呼吸道病毒性病原谱及流行规律研究~~
【分类号】：R440;R56
【正文快照】： 2010年全球约1200万人因急性呼吸道感染入院,约300万人罹患严重急性呼吸道感染,研究显示,每年约有156万儿童死于急性呼吸道感染[1],2009~2011年15岁以上成年人急性严重呼吸道感染比例占(Severe acute respiratory infection,SA-RI)SARI总病例的27%[2],由于呼吸道致病微生物感

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