DWI结合ADC值鉴别诊断睾丸生殖细胞瘤

发布时间：2018-01-20 23:15

本文关键词： 表观扩散系数扩散加权成像睾丸肿瘤肿瘤生殖细胞和胚胎性　出处：《中国医学影像技术》2017年01期 　论文类型：期刊论文

【摘要】：目的探讨DWI结合ADC值鉴别诊断睾丸精原细胞瘤和非精原细胞瘤的价值。方法回顾性分析经手术及病理证实的22例睾丸生殖细胞瘤患者,其中精原细胞瘤10例,非精原细胞瘤12例。均行MRI平扫、DWI扫描,并测量不同肿瘤实质部分的ADC值,采用独立样本t检验比较精原细胞瘤和非精原细胞瘤ADC值的差异。结果 10例精原细胞瘤的DWI多呈均匀性高信号,平均ADC值为(0.63±0.12)×10~(-3)mm~2/s,12例非精原细胞瘤的DWI多呈不均匀高信号,平均ADC值为(0.98±0.22)×10~(-3)mm~2/s,二者的ADC值差异有统计学意义(t=4.61,P0.01)。结论 DWI结合ADC值有助于鉴别精原细胞瘤与非精原细胞瘤。
[Abstract]:Objective to investigate the value of DWI combined with ADC in differential diagnosis of testicular seminoma and non-seminoma. Methods 22 cases of testicular germ cell tumor proved by operation and pathology were retrospectively analyzed. Among them, 10 cases of seminoma and 12 cases of non-seminoma were examined by MRI plain scan, and the ADC values of different tumor parenchyma were measured. The difference of ADC between seminoma and non-seminoma was compared by t-test of independent samples. Results the DWI of 10 cases of seminoma showed homogeneity and high signal intensity. The average ADC value was 0.63 卤0.12) 脳 10 ~ (-3) mm ~ (-2) / s ~ (-1). The DWI of 12 cases of non-seminoma showed heterogenous hyperintensity. The average ADC value was 0.98 卤0.22) 脳 10 ~ (-3) mm ~ (-2) / s, and the difference of ADC value between the two groups was statistically significant (t = 4.61). Conclusion DWI combined with ADC value is helpful in differentiating seminoma from non-seminoma.
【作者单位】：郑州大学第一附属医院磁共振科;
【分类号】：R445.2;R737.21
【正文快照】： 睾丸肿瘤中约95%为生殖细胞源性肿瘤,分为精原细胞瘤和非精原细胞瘤(包括胚胎性癌、卵黄囊瘤、绒毛膜癌、畸胎瘤及这些肿瘤的混合型),其中精原细胞瘤约占35%~50%[1-2]。精原细胞瘤对放疗敏感,而非精原细胞瘤治疗以手术和化疗为主,两者的鉴别诊断对于指导临床治疗具有重要价值[

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