本院2005-2015年输血过敏性不良反应统计分析

发布时间：2018-02-26 09:22

本文关键词： 输血反应过敏紫癜瘀斑荨麻疹　出处：《中国输血杂志》2017年03期 　论文类型：期刊论文

【摘要】：目的调查分析发生过敏性输血反应的原因,探究其处理措施,降低过敏性输血不良反应的发生。方法对本院10年住院患者发生输血过敏反应进行回顾性总结分析。结果本院76 703人输血,发生输血过敏反应93例(0.12%)。不同的血液成分中悬浮红细胞、去白悬浮红细胞、洗涤红细胞、血小板、冷沉淀以及血浆过敏反应发生率分别为0.11%、0.08%、0.00%、0.21%、0.10%、0.13%。过敏性输血反应中轻度过敏、重度过敏、休克、紫癜构成比分别为88.2%、7.5%、3.2%、1.1%;输血0次和1次以上的患者再次输血过敏反应发生率分别为0.08%、0.17%;男女输血患者过敏发生率分别为0.10%、0.15%;1例过敏性紫癜是由于患者缺乏Ig A导致的。结论血小板过敏反应发生率最高,洗涤红细胞最低;输血次数越多过敏反应发生率越高,女性输血过敏反应发生率高于男性;对过敏反应的患者,再次输血选择洗涤红细胞或洗涤血小板,慎输血浆;对检出Ig A抗体的患者,选Ig A缺乏献血者的血液。
[Abstract]:Objective to investigate and analyze the causes of allergic blood transfusion reaction and explore the treatment measures. Methods the allergic reaction of blood transfusion in our hospital for 10 years was analyzed retrospectively. Results 76,703 patients in our hospital received blood transfusion. Blood transfusion allergic reaction occurred in 93 cases. The incidence of suspended red blood cells, white suspended red blood cells, washed red blood cells, platelets, cryoprecipitation and plasma anaphylaxis in different blood components were 0.110.88 and 0.000.210.100.13.The allergic blood transfusion reactions were mild allergies. Severe allergies, shock, The constituent ratio of purpura was 88.27.5 and 3.2and 1.1, the rate of anaphylaxis was 0.080.17in the patients with blood transfusion for 0 times and more than one time, and the anaphylaxis rate was 0.100.15% in male and female transfusion patients, which was caused by lack of IgA in the patients. Conclusion the incidence of platelet allergic reaction is the highest. The incidence of allergic reaction in women was higher than that in men, and in patients with allergic reactions, washing red blood cells or washed platelets were used again and plasma was carefully injected. For patients with IgA antibodies, blood samples from donors with Ig A deficiency were selected.
【作者单位】：郑州市第七人民医院;河南省红十字血液中心;
【分类号】：R457.13

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