非肿块型乳腺癌的超声表现与其病理特征的相关性研究

发布时间：2018-02-26 22:11

本文关键词： 乳腺肿瘤超声检查多普勒彩色　出处：《中国临床医学影像杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的:初步探讨非肿块型乳腺癌的超声表现与其病理特征的相关性。方法:选取病理证实的69例女性乳腺病变患者,共69个非肿块型乳腺癌。非肿块型乳腺癌的超声图像表现分为导管扩张型、片状低回声型、局部结构紊乱型及混合改变型。通过Pearson卡方检验或Fisher精确检验比较不同超声类型的病理特征。结果:导管扩张型中导管原位癌(DCIS)所占比例为81.8%,明显大于其他3种类型(P0.001);混合回声型中无DCIS,均为浸润癌;局部结构紊乱型中只有1例为DCIS(9.1%)。导管扩张型(72.7%)及混合改变型(68.8%)中人表皮生长因子受体-2(HER-2)阳性率大于片状低回声型(40.0%)及局部结构紊乱型(27.3%),总体差异有统计学意义(P=0.035)。混合改变型(50.0%)较导管扩张型(0.0%)、片状低回声型(26.7%)及局部结构紊乱型(27.3%)腋窝淋巴结转移更常见,总体差异有统计学意义(P=0.019)。结论:非肿块型乳腺癌的超声表现类型与其病理组织类型、HER-2表达情况及腋窝淋巴结转移有一定相关性。
[Abstract]:Objective: to explore the correlation between ultrasonic findings and pathological features of non-mass breast cancer. Methods: 69 cases of female breast lesions confirmed by pathology were selected. There were 69 non-mass breast cancers. The ultrasonic findings of non-mass breast cancer were as follows: ductal dilatation type, lamellar hypoechoic type. The pathological features of different types of ultrasound were compared by Pearson chi-square test or Fisher precise test. Results: the proportion of ductal carcinoma in situ was 81.8%, which was significantly higher than that of the other three types of ductal dilatation. There was no DCIS in mixed echo type, all of them were invasive carcinoma. The positive rate of human epidermal growth factor receptor (EGF receptor -2HER-2) was higher than that of flake hypoechoic type (40.0%) and local structure disorder type (27.3%). The overall difference was statistically significant (P = 0.035), and the positive rate of human epidermal growth factor receptor (-2HER-2) was higher than that of lamellar hypoechoic type (40.0%) and that of local structure disorder type (27.3%) was higher than that of local ectopic type (72.7%) and mixed type (68.8%). The axillary lymph node metastasis was more common in the mixed type than in the dilated ductal type (0.010%), the lamellar hypoechoic type (26.7%) and the local structural disorder type (27.3%). Conclusion: the ultrasonographic manifestations of non-mass breast cancer are correlated with the expression of HER-2 and axillary lymph node metastasis.
【作者单位】：江苏省省级机关医院超声诊断科;
【分类号】：R445.1;R737.9

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