小肝癌的超声造影与声脉冲辐射力成像的临床研究

发布时间：2018-03-01 09:25

本文关键词： 小肝癌超声造影时间强度曲线声脉冲辐射力成像 VTQ　出处：《中国医学计算机成像杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的:探讨超声造影时间-强度曲线与声脉冲辐射力成像(ARFI)在小肝癌诊断中的应用研究。方法:32例肝右叶小肝癌患者纳入研究,癌灶与灶旁实质区同步进行超声造影时间强度曲线分析及ARFI检查。造影定量分析应用Contrast Dynamic软件脱机分析。ARFI检查分别测量病灶区域和同一深度肝脏实质的VTQ值,并进行统计学分析。结果:32例小肝癌灶与灶旁实质区肝组织的Peak、TP和VTQ值均有统计学差异(P0.05)。肝癌病灶VTQ值与超声造影参数Peak呈正相关(r=0.612,P0.05)。ROC曲线分析示肝癌病灶Peak38.95%时特异性为65.6%,敏感性为73.7%,曲线下面积为0.789,可信区间为0.685~0.894。结论:ACQ时间强度曲线分析的Peak与声脉冲辐射力成像测得的VTQ值可对小肝癌诊断提供依据,并且两者间具有很好的相关性。
[Abstract]:Objective: to investigate the application of time-intensity curve of contrast-enhanced ultrasound and acoustic pulse radiography (ARFI) in the diagnosis of small hepatocellular carcinoma (HCC). Methods: 32 patients with small liver cancer in right lobe of liver were included in the study. Contrast-enhanced time-intensity curve analysis and ARFI examination were performed simultaneously between the lesion and the para-focal parenchyma. The VTQ values of the focus area and the liver parenchyma of the same depth were measured by Contrast Dynamic software offline analysis .ARFI respectively. Results there were significant differences in TP and VTQ between small hepatocellular carcinoma and para-focal parenchymal liver tissue in 32 cases of small liver cancer. The VTQ value of liver cancer focus was positively correlated with the parameters of contrast-enhanced ultrasound (Peak). The curve analysis of Peak38.95% showed that there was a positive correlation between the VTQ value of small liver cancer focus and the liver tissue of para-focal parenchymal area. The sensitivity is 73.7, the area under the curve is 0.789, and the confidence interval is 0.6850.894.Conclusion the Peak obtained by the time intensity curve analysis and the VTQ value measured by acoustic pulse radiography can provide the basis for the diagnosis of small liver cancer. And there is a good correlation between the two.
【作者单位】：延边大学附属医院影像二科;
【分类号】：R445.1;R735.7

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