许莫氏结节与腰椎间盘退变分型的相关性研究

发布时间：2018-03-03 02:00

本文选题：许莫氏结节　切入点：腰椎间盘退变类型　出处：《广州中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:分析许莫氏结节在腰椎MRI中的性别、年龄、位置等分布特点,探讨其与腰椎间盘退变类型的相关性,以提高对许莫氏结节发病机制的认识水平。方法:选取2016年9月1日至2016年12月1日期间在广州中医药大学第一附属医院接受腰椎MRI检查的患者781例,记录其年龄、性别、结节发生部位、结节MRI信号类型及其邻近椎间盘退变类型(正常/膨出/突出/脱出/HIZ/modic改变)等相关信息,保存患者的影像学图像资料,并对其相关数据进行统计分析。结果:在参与调查的781(男:376,女:405)例病人中发现许莫氏结节患者93(男性:54,女性:39)例,许莫氏结节的发生率为11.9%；许莫氏结节在男性中的发生率为14.4%,女性9.6%(P0.05),差异有统计学意义；年龄与许莫氏结节无明显相关性(P0.05)；许莫氏结节多发于L3椎体上缘(4.1%),其次为L2、L5椎体上缘(3.8%),然后依次为L4椎体下缘(3.7%)、L4椎体上缘(3.6%),差异有统计学意义；许莫氏结节多发生于上终板(3.3%),下终板的发生率为2.4%,差异有统计学意义；93例许莫氏结节患者共计465个腰椎间盘节段,退变255个,许莫氏结节在腰椎间盘退变中的发生率较高(47.8%),差异有统计学意义,许莫氏结节MRI信号类型与腰椎间盘退变无关；膨出127个,许莫氏结节在腰椎间盘膨出中的发生率较高(48%),差异有统计学意义,双侧或单侧终板发生许莫氏结节在腰椎间盘膨出中的发生率之间的差异无显著性意义；许莫氏结节与腰椎间盘突出、脱出、HIZ无明显相关性(P0.05)；modic改变64个,许莫氏结节在腰椎modic改变中的发生率较高(73.4%),差异有统计学意义。结论:本组病例腰椎许莫氏结节的发生率男性大于女性,好发于L2、3椎体上缘、L4椎体上下缘及L5椎体上缘,许莫氏结节上终板的发生率高于下终板；许莫氏结节的发生与腰椎间盘退变、膨出有明显关系,并与modic改变密切相关；
[Abstract]:Objective: to analyze the sex, age and location of Schumo's tubercle in lumbar MRI, and to explore the correlation between it and the type of degeneration of lumbar intervertebral disc. Methods: from September 1st 2016 to December 1st 2016, 781 patients underwent lumbar MRI examination in the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine, and their age and sex were recorded. The location of nodule, the type of MRI signal and adjacent disc degeneration (normal / bulging / protruding / protruding / protruding / protruding / protruding / reproducing / HIZ / modic change) were used to preserve the imaging images of the patients. Results: among the 781 patients (male: 376, female: 405) who participated in the investigation, 93 cases (male: 54, female: 39) with Humo's nodule were found. The incidence of Xu Mo's nodule was 11.9%, the incidence of Xu Mo's nodule in male was 14.4%, the female's rate was 9.6% (P 0.05), the difference was statistically significant. There was no significant correlation between age and Xumo's tubercle (P0.05), Xumo's tubercle was mainly located in the upper margin of L3, followed by L2, L5, 3.8T, and then L4, 3.7C, L4, 3.6T (P < 0.05). Most of the Schumo's nodules occurred in the upper end plate and the inferior end plate. The incidence of the lower end plate was 2.4. The difference was statistically significant in 93 patients with Xu Mo's tubercle with 465 segments of lumbar intervertebral disc, with 255 degeneration. The incidence of Schumo's nodules in lumbar disc degeneration was higher than that in lumbar disc degeneration (47.8%), the difference was statistically significant. The MRI signal type of Xumo's tubercle was not related to the degeneration of lumbar intervertebral disc. The incidence of Xumo's tubercle in lumbar disc herniation was higher than that in control group, the difference was statistically significant, but there was no significant difference between bilateral or unilateral endplates in the incidence of herniation of lumbar intervertebral disc. There was no significant correlation between Xu Mo's tubercle and lumbar disc herniation. There was no significant correlation between Hiz and 64 changes in modic (P 0.05). The incidence of Schumo's nodule in lumbar modic was higher than that in female, and the difference was statistically significant. Conclusion: the incidence of Schumo's tubercle in male is higher than that in female, and it usually occurs in upper and lower margin of L4 and upper edge of L5 vertebra. The incidence of superior end plate of Schumo's tubercle was higher than that of inferior endplate, and the occurrence of Schumo's tubercle was significantly related to lumbar disc degeneration and herniation, and was closely related to the change of modic.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R681.5;R445.2

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