前列腺癌磁共振波谱与扩散加权成像诊断效能的Meta分析

发布时间：2018-03-08 12:11

本文选题：前列腺肿瘤　切入点：磁共振成像　出处：《中国医学影像学杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的探讨磁共振波谱成像(MRS)与扩散加权成像(DWI)对我国人群前列腺癌的诊断价值。资料与方法运用Review Manager 5.2和Meta-Disc软件对近10年有关我国人群使用MRS及DWI检查对前列腺癌的诊断价值的文献进行Meta分析,计算MRS及DWI的敏感度、特异度、诊断比值比和受试者工作特性曲线下面积,按QUADAS法评价纳入研究的质量。结果符合纳入标准的文献共计10篇,Meta分析中异质性检验敏感度、特异度均不存在异质性,可以进行合并,合并结果显示,DWI、MRS的受试者工作特性曲线下面积分别为0.8979、0.9302,敏感度分别为0.83、0.87,特异度分别为0.84、0.86,诊断比值比分别为22.71、41.31。结论MRS对前列腺癌的诊断价值及诊断敏感度、特异度均较DWI高,当前列腺癌在DWI上表现不典型或诊断不明确时,可参考MRS检查结果。本文用定量系统评价的方法研究DWI及MRS对前列腺癌的诊断价值,为采用影像学方法诊断前列腺癌提供循证医学证据。
[Abstract]:Objective to evaluate the diagnostic value of magnetic resonance spectroscopy imaging (MRS) and diffusion-weighted imaging (DWI) in prostate cancer in Chinese population. Data and methods Review Manager 5.2 and Meta-Disc software were used to examine the prostate of Chinese population with MRS and DWI in the past 10 years. The diagnostic value of cancer was analyzed by Meta. The sensitivity, specificity, diagnostic ratio ratio and area under the operating characteristic curve of MRS and DWI were calculated. The quality of the study was evaluated by QUADAS method. There is no heterogeneity in the specificity, so it can be merged. The combined results showed that the area under the operating characteristic curve of DWIRS was 0.8979 / 0.9302, the sensitivity was 0.83n0.87, the specificity was 0.84n0.86, and the diagnostic ratio was 22.71g / 41.31.Conclusion the diagnostic value and sensitivity of MRS in the diagnosis of prostate cancer are higher than that of DWI. The diagnostic value of DWI and MRS in the diagnosis of prostate cancer was studied by quantitative and systematic evaluation method, when the diagnosis of prostate cancer was not typical or diagnosed clearly on DWI, and the results of MRS examination could be consulted. To provide evidence-based medical evidence for imaging diagnosis of prostate cancer.
【作者单位】：南昌大学第一附属医院影像科;南昌大学第一附属医院疼痛科;
【基金】：江西省教育厅基金(GJJ160128)
【分类号】：R445.2;R737.25

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