829例婴幼儿腹泻轮状病毒抗原检测分析

发布时间：2018-03-15 03:25

本文选题：A组轮状病毒　切入点：婴幼儿腹泻　出处：《热带医学杂志》2017年03期 　论文类型：期刊论文

【摘要】：目的对婴幼儿腹泻患者进行粪便A组轮状病毒抗原检测,以了解A组轮状病毒(RV-A)感染情况及流行病学特征,为临床诊断提供依据。方法收集广州医科大学附属第二医院2014年1月至2015年12月因腹泻就诊的门诊和住院患儿粪便标本,采用胶体金免疫层析法检测A组轮状病毒。结果在829例患儿粪便标本中共检出RV-A阳性175例,阳性率为21.1%。全年均能检出RV-A阳性,以秋季阳性检出率最高,占全年阳性率的81.7%。不同性别腹泻患儿的阳性检出率差异无统计学意义(P0.05);不同年龄组中以0.5~1岁和1~2岁组的阳性检出率最高,差异有统计学意义(P0.05)。结论 A组轮状病毒是婴幼儿腹泻的重要病原体,以秋季高发,提示临床加强腹泻婴幼儿粪便中RV-A检测,对临床早诊断、早治疗和预防并发症有重要意义。
[Abstract]:Objective to detect group A rotavirus antigen in feces of infantile diarrhea patients, and to understand the infection and epidemiological characteristics of group A rotavirus virus (RV-A). Methods fecal specimens of outpatients and hospitalized children with diarrhea from January 2014 to December 2015 were collected from the second affiliated Hospital of Guangzhou Medical University. Results the positive rate of RV-A was 21. 1 in 829 fecal specimens of children with rotavirus. The positive rate of RV-A was 21. 1. The positive rate of RV-A was the highest in autumn. The positive rate was 81.7% in the whole year. There was no significant difference in the positive rate among the children with diarrhea of different sex (P 0.05), but the positive rate was the highest in the groups of 0.5 ~ 1 and 1 ~ 2 years of age. Conclusion Group A rotavirus is an important pathogen of infantile diarrhea. The high incidence of rotavirus in autumn suggests that it is important to strengthen the detection of RV-A in feces of infants with diarrhea in clinical early diagnosis, early treatment and prevention of complications.
【作者单位】：深圳市宝安区人民医院检验科;广州医科大学附属第二医院检验科;
【基金】：广州市医药卫生科技项目(20141A011082)
【分类号】：R725.1;R446

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