磁共振扩散张量成像评价女性盆底肌加龄性变化规律的可行性研究

发布时间：2018-03-17 17:14

本文选题：盆底肌　切入点：磁共振扩散张量成像　出处：《中国医学计算机成像杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的:通过分析女性盆底肌磁共振扩散张量成像(DTI)参数值随年龄的变化,探讨DTI评价女性盆底肌加龄性变化规律的可行性。方法:研究对象为42名无盆底功能障碍的女性,行常规磁共振(MRI)和DTI扫描,将DTI原始数据于ADW4.5工作站上进行后处理,分别测量双侧肛提肌及闭孔内肌的表观弥散系数(ADC)、各向异性分数(FA)、容积比各向异性(VRA),分析肛提肌、闭孔内肌的DTI参数值随年龄的变化趋势。结果:青年组、中年组及老年组的肛提肌FA值分别为0.29±0.05,0.33±0.06和0.30±0.06;闭孔内肌的FA值分别为0.33±0.03,0.35±0.03和0.34±0.02。青年组和中年组间的肛提肌和闭孔内肌的FA值差异均有统计学意义(P=0.007,0.026)。各年龄组间肛提肌和闭孔内肌的ADC和VRA均无统计学差异。结论:DTI的参数值FA值与年龄存在关联,DTI可以评价女性盆底肌的加龄性变化规律。
[Abstract]:Objective: to explore the feasibility of DTI in evaluating the age of female pelvic floor muscles by analyzing the changes of the parameters of magnetic resonance diffusion imaging (DTI) of female pelvic floor muscles with diffusive magnetic resonance imaging. Methods: 42 women without pelvic floor dysfunction were enrolled in the study. The original data of DTI were postprocessed on ADW4.5 workstation. The apparent diffusion coefficients of the levator ani muscle and the internal obturator muscle were measured, and the anisotropic fraction and volume specific anisotropy were measured to analyze the levator ani muscle. Trends of DTI parameters of Intraoblatus obturator muscle with Age. Results: young group, The FA values of levator ani muscle were 0.29 卤0.05 0.33 卤0.06 and 0.30 卤0.06 in middle age group and aged group respectively, and the FA value of obturator internal muscle were 0.33 卤0.03 卤0.03 and 0.34 卤0.02 respectively. There were significant differences in FA value of levator ani muscle and internal obturator muscle between young group and middle age group. Conclusion there is a correlation between FA value and age of female pelvic floor muscle.
【作者单位】：潍坊医学院附属医院影像中心;滨州医学院影像学研究所;
【基金】：国家自然科学基金项目(81171303,30470518) 山东省自然科学基金(ZR2009CL046,ZR2010HQ029,ZR2013HQ020) 山东省优秀中青年科学家科研奖励基金(BS2012YY038) 山东省卫生厅科技发展项目(2011WSB29009,2011HW067) 滨州医学院山东省特色重点学科山东省科技攻关项目(2007GG30002032,2008GG30002004) 潍坊医学院博士科研启动基金(2009);潍坊医学院大学生科技创新基金(KX2015011)~~
【分类号】：R445.2;R711.5

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