磁共振扩散峰度成像在乳腺良恶性病变鉴别诊断中的价值

发布时间：2018-03-18 06:18

本文选题：乳腺肿瘤　切入点：扩散峰度成像　出处：《放射学实践》2017年02期 　论文类型：期刊论文

【摘要】：目的:探讨磁共振扩散峰度成像(DKI)在乳腺良恶性病变鉴别诊断中的价值。方法:回顾性分析经穿刺活检或手术病理证实的45例乳腺病变患者的病例资料。45例患者共53个病灶,其中良性病灶31个(23例),恶性病灶22个(22例),所有患者均行双侧乳腺的常规MRI检查及DKI扫描,通过后处理工作站获得乳腺良、恶性病变组织的平均峰度(MK)、轴向峰度(AK)、径向峰度(RK)值。采用Mann-Whitney U秩和检验比较MK、AK及RK值在乳腺良、恶性病变中的统计学差异。采用受试者操作特性(ROC)曲线评价上述参数对乳腺良、恶性病变的诊断效能。结果:乳腺恶性病变的MK、AK及RK值均明显高于良性病变,且差异均具有统计学意义(P均0.001)。MK、AK、RK的ROC曲线下面积(AUC)分别是0.886、0.930、0.881;良恶性诊断界值分别为0.45900、0.7250、0.3430;敏感度分别为95.6%、86.4%、90.9%;特异度分别为64.5%、87.1%、66.7%。结论:DKI获得的MK、AK、RK在乳腺良恶性病变的鉴别诊断中具有一定的价值。
[Abstract]:Objective: to evaluate the value of Mr diffusion kurtosis imaging (DKI) in the differential diagnosis of benign and malignant breast lesions. There were 31 benign lesions in 23 cases and 22 malignant lesions in 22 cases. All the patients underwent routine MRI examination and DKI scan of bilateral mammary glands, and good breast was obtained by post processing workstation. The mean kurtosis, axial kurtosis and radial kurtosis of malignant lesions were measured by Mann-Whitney U rank sum test. To evaluate the diagnostic efficacy of the above parameters in benign and malignant breast lesions, the MKAK and RK values of malignant breast lesions were significantly higher than those of benign lesions. The area under the ROC curve was 0.8860.930 / 0.881respectively; the diagnostic threshold of benign and malignant was 0.459000.250 / 0.3430; the sensitivity was 95.60.64; and the specificity was 64.57.77.76.7.Conclusion the diagnostic threshold of MKKI for benign and malignant lesions is 0.45900 and 0.7250 / 0.3430, and the specificity is 64.57.1and 66.7 respectively. Conclusion the MKKK obtained by President DKI can be used in the differential diagnosis of benign and malignant breast and breast diseases. [WT5 "HZ] [WT5HZ] [WT5" BZ] [WT5 "HZ] [WT5" HZ] [WT5BZ] [WT5BZ] [WT5 "HZ]. Break has certain value.
【作者单位】：郑州大学第一附属医院磁共振科;
【分类号】：R737.9;R445.2

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