9013例输血者不规则抗体筛查结果及意义

发布时间：2018-03-28 21:36

本文选题：输血　切入点：不规则抗体　出处：《首都医科大学学报》2017年05期

【摘要】：目的分析9 013例输血者不规则抗体筛查结果,并探讨不规则抗体筛查的临床意义。方法回顾性分析自2013年7月至2016年8月于首都医科大学附属北京朝阳医院接受输血的病人9 013例,应用微柱凝胶技术筛查不规则抗体,并进行鉴定。统计分析不规则抗体的阳性率、分布及不同科室中不规则抗体的阳性率,另外分析性别及输血/妊娠史对不规则抗体阳性率的影响。结果 9 013例输血者的血液标本中不规则抗体的阳性率为0.63%(57/9 013),主要为Rh型,占42.11%(24/57);其次为MNS型,占24.56%(14/57);其他类型及所占比例分别为Lewis系统(10.53%)、Kidd系统(8.77%)。P系统(5.26%)及其他(8.77%)。外科输血者不规则抗体检出率为1.06%(14/1 321),高于其他科室的0.59%(43/7 692),差异具有统计学意义(P0.05)。女性输血者中不规则抗体的阳性率为0.94%(30/3 187),明显高于男性病人的0.46%(27/5 826),且差异具有统计学意义(P0.05)。有输血/妊娠史输血者的血浆中不规则抗体的阳性率为0.85%(34/3 986),显著高于无输血/妊娠史输血者的0.46%(23/5 027)(P0.05)。结论输血前对不规则抗体进行筛查对于提高输血安全性具有重要意义,为筛查呈阳性病人提供适合的血型,从而降低临床免疫溶血事件的发生,提高输血的有效性。
[Abstract]:Objective to analyze the results of irregular antibody screening in 9 013 cases of blood transfusion. Methods from July 2013 to August 2016, 9 013 patients receiving blood transfusion in Beijing Chaoyang Hospital affiliated to Capital Medical University were analyzed retrospectively. Microcolumn gel technique was used to screen irregular antibodies. The positive rate of irregular antibody, the distribution of irregular antibody and the positive rate of irregular antibody in different departments were analyzed statistically. In addition, the influence of sex and blood transfusion / pregnancy history on the positive rate of irregular antibody was analyzed. Results the positive rate of irregular antibody in blood samples of 9 013 blood transfusion patients was 0.6357 / 9 013, mainly Rh type, accounting for 42.1111 / 24 / 57%, followed by MNS type. The rate of irregular antibodies in surgical transfusions was 1.0614 / 1321g, which was higher than that in other departments (0.5943 / 7.692g, P = 0.5943 / 7.692p, P = 8.775.26) and 8.777.21%, respectively. The difference was statistically significant (P < 0.05). There was no significant difference in blood transfusions among female blood transfusions (P > 0.05), and the results showed that the percentage of irregular antibodies in surgical transfusions was 1.0614% / 1321%, which was higher than that in other departments (0.5943 / 7 692%), and the difference was statistically significant (P 0.05). The positive rate of regular antibody was 0.9430 / 3 1877, which was significantly higher than that of male patients (0.46 / 5826), and the difference was statistically significant (P 0.05). The positive rate of irregular antibody in blood transfusion / pregnancy history was 0.85 / 343.986g, which was significantly higher than that without blood transfusion / pregnancy history. Conclusion screening for irregular antibodies before blood transfusion is of great significance in improving the safety of blood transfusion. To provide suitable blood type for screening positive patients, so as to reduce the occurrence of clinical immune hemolysis events and improve the effectiveness of blood transfusion.
【作者单位】：首都医科大学附属北京朝阳医院输血科;
【分类号】：R446.6;R457.1

【相似文献】