FA值、ADC值与腰骶丛脊神经根受压程度的相关性研究

发布时间：2018-03-30 09:18

本文选题：腰骶丛神经根压迫症　切入点：磁共振扩散张量成像　出处：《长江大学》2017年硕士论文

【摘要】：目的:探讨MR扩散张量成像(Diffusion Tensor Imaging,DTI)技术的各向异性分数(Fractional Anisotropy,FA)以及表观扩散系数(Apparent Diffusion Coefficient,ADC)与腰骶丛脊神经根受压程度的关系,评价DTI技术在腰骶丛脊神经根受压程度中的诊断价值。方法:选取70例腰椎间盘突出患者行常规磁共振(Magnetic Resonance Imaging,MRI)及DTI检查,在常规轴位T2WI上依据Lindblon分型法获得L_5神经根受压程度的Lindblon分型(共4级),在DTI图像上测量L_5神经根的FA值、ADC值,分析Lindblon分型与FA值、ADC值的关系,并进行双侧L3至S1神经根扩散张量纤维束成像(Diffusion Tensor Tractography,DTT)。结果:(1)患侧L_5神经根平均FA值显著低于健侧(t=-4.416,p0.01),患侧L_5神经根平均ADC值高于健侧(t=3.334,p0.05);(2)各级神经根平均FA值、ADC值的差异有高度统计学意义(F=50.347,P0.01;F=53.572,P0.01);(3)经Spearman秩相关分析显示神经根受压Lindblon分级与FA值呈负相关(rs=0.970,p0.01),与ADC值呈正相关(rs=-0.963,p0.01)。结论:(1)3.0T MRI扩散张量和扩散张量纤维束成像可以用来显示腰骶部脊神经根;(2)在3.0T MRI扩散张量纤维束成像(DTT)图上可以清楚、完整地显示大部分患者的脊神经根;(3)FA值、ADC值可以反映神经根受压程度,且随着受压程度的加重,FA值降低,ADC值升高。
[Abstract]:Objective: to investigate the relationship between anisotropic fractional fraction (Fractional fractional fraction) and apparent diffusion coefficient (Apparent Diffusion efficient) of diffused Tensor imaging (DTI) and the degree of compression of lumbosacral plexus spinal nerve root. To evaluate the diagnostic value of DTI technique in the degree of compression of lumbar and sacral plexus nerve root. Methods: 70 patients with lumbar disc herniation were selected for routine magnetic Resonance imaging and DTI examination. The Lindblon classification of the compression degree of L _ 5 nerve root was obtained by Lindblon classification on conventional T2WI. The FA value and ADC value of L _ 5 nerve root were measured on DTI images, and the relationship between Lindblon classification and FA value was analyzed. Bilateral L3 to S1 nerve root diffusion Zhang Liang fiber bundle imaging was performed on Diffusion Tensor tractography. Results the average FA value of L5 nerve root in affected side was significantly lower than that in healthy side, and the average ADC value of affected L5 nerve root was higher than that of healthy side t3.334 (p 0.05). The Spearman rank correlation analysis showed that the Lindblon grade of nerve root compression was negatively correlated with FA value and had a positive correlation with ADC value. Conclusion the diffused Zhang Liang of MRI diffusing Zhang Liang and the diffusive Zhang Liang fiber bundle imaging can be used to display lumbosacral sacral bundles. Spinal nerve root 2) can be clearly seen on 3.0T MRI diffusion Zhang Liang fiber bundle imaging. The results showed that the FA value and ADC value of most patients could reflect the degree of nerve root compression, and the ADC value increased with the increase of the compression degree.
【学位授予单位】：长江大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R445.2;R681.53

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