降钙素原与中性粒细胞淋巴细胞计数比对心内科住院患者病原菌感染的早期诊断研究

发布时间：2018-04-04 18:21

  本文选题：降钙素原　切入点：中性粒细胞　出处：《中华医院感染学杂志》2017年19期

【摘要】：目的探讨降钙素原与中性粒细胞淋巴细胞计数比对心血管疾病住院患者病原菌感染的早期诊断价值。方法选择2014年1月-2016年10月医院心内科及干部病房住院的652例可能有病原菌感染的老年患者作为研究对象,按照病原菌培养结果分为感染组476例和非感染组176例,分析降钙素原(PCT),白细胞计数(WBC),中性粒细胞计数(NE)和NLR四个指标针对感染的诊断价值。结果 652名患者的病原菌培养结果中,阳性476例占73.01%;阴性176例,占26.99%,感染部位以呼吸道和泌尿系统为主,共分离病原菌476株,其中革兰阳性菌350株占73.53%,革兰阳性菌126株占26.47%,未出现两种以上病原菌的合并感染;感染组WBC,NE,PCT和NLR分别为(14.13±4.32)×109/L,(0.73±0.13)×109/L,(1.25±0.42)ng/ml,(2.59±0.75),显著高于非感染组(10.52±3.95)×109/L,(0.58±0.14)×109/L,(0.40±0.13)ng/ml,(1.42±0.62),PCT的灵敏度和特异度最高,在PCT和NLR两个指标并联使用的情况下,灵敏度进一步增高。结论心血管疾病老年患者感染以呼吸与泌尿系统为主,病原菌分布与常规院内感染分布类似,在PCT和NLR两个指标并联使用的情况下,灵敏度增高,适合对心血管疾病老年患者的病原菌感染进行早期诊断。
[Abstract]:Objective to investigate the early diagnostic value of procalcitonin / neutrophil lymphocyte count ratio in the early diagnosis of pathogenic bacteria infection in patients with cardiovascular disease.Methods from January 2014 to October 2016, 652 elderly patients with possible pathogenic bacteria infection were selected from cardiology department and cadre ward of hospital from January 2014 to October 2016. According to the results of pathogen culture, they were divided into infection group (476 cases) and non-infection group (176 cases).To analyze the diagnostic value of procalcitonin (PCT), leukocyte count (WBC), neutrophil (neo) and NLR in the diagnosis of infection.Results of the 652 patients, 476 were positive (73.01), 176 (26.99) were negative, and 476 were isolated from respiratory tract and urinary system.鍏朵腑闈╁叞闃虫，

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