定量磁共振动态增强诊断不典型乳腺癌与纤维腺瘤的研究

发布时间：2018-04-09 05:02

本文选题：动态对比增强　切入点：定量参数　出处：《青海大学》2017年硕士论文

【摘要】：目的探讨磁共振动态定量参数Ktrans、Kep、Ve、Vp对不典型乳腺癌和纤维腺瘤的鉴别诊断价值。方法分析经病理证实的乳腺癌30例和纤维腺瘤32例的血流动力学参数Ktrans、Ve、Kep、Vp值,比较不典型乳腺癌、纤维瘤中各参数的统计学差异。结果不典型乳腺癌组Ktrans、Kep、Ve、Vp值分别为(1.487±0.545)min-1、(0.697±0.022)min-1、0.781±0.325、0.260±0.130,纤维腺瘤组Ktrans、Kep、Ve、Vp值分别为(0.639±0.266)min-1、(0.302±0.160)min-1、0.658±0.248、0.330±0.152;Ktrans、Ve、Kep在两组差异有统计学意义(P=0,P=0.031,P=0),Vp在两组间差异没有统计学意义(P=0.398)。Ktrans、Kep、Ve的敏感度分别为91.4%、80%、45.7%,特异度分别为86.7%、86.7%、83.8%。结论Ktrans、Kep在不典型乳腺癌与纤维腺瘤的鉴别中有较高的诊断价值,可作为鉴别诊断的参考,Ve值可与其他参数联合应用,提高诊断效能。
[Abstract]:Objective to explore the magnetic resonance dynamic quantitative parameters of Ktrans, Kep, Ve, differential diagnosis of atypical breast cancer and fibroadenoma Vp. Methods by analyzing the hemodynamic parameters of Ktrans, 32 cases of fibroadenoma and 30 cases of pathologically confirmed breast cancer Ve, Kep, Vp, comparison of atypical breast cancer, statistically significant differences between the various parameters fibroma. The atypical breast cancer group, Ktrans, Kep, Ve, Vp respectively (1.487 + 0.545) min-1, (0.697 + 0.022) min-1,0.781 + 0.325,0.260 + 0.130, Kep, Ve in fibroadenoma group Ktrans, Vp = (0.639 + 0.266) min-1, (0.302 + 0.160) min-1,0.658 + 0.248,0.330 + 0.152; Ktrans, Ve, Kep had significant difference between the two groups (P=0, P=0.031, P=0, Vp) in the difference between the two groups was not statistically significant (.Ktrans, P=0.398) Kep, the sensitivity of Ve was 91.4%, 80%, 45.7%, specificity was 86.7%, 86.7% respectively, 83.8%. conclusion Ktrans Kep, in a typical dairy The diagnostic value of adenocarcinoma and fibroadenoma is of high diagnostic value. It can be used as a reference for differential diagnosis. The Ve value can be combined with other parameters to improve the diagnostic efficiency.

【学位授予单位】：青海大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.9;R445.2

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