血型、性别及输血次数与血小板抗体阳性率关系的探讨

发布时间：2018-04-11 15:19

本文选题：血小板抗体 + 血型　；参考：《中国输血杂志》2017年07期

【摘要】：目的探讨与分析血型、性别、输血次数与血小板抗体阳性率的关系。方法对2016年1月1日-2016年12月31日5 745名输血患者进行固相凝集法检测血小板抗体,统计血小板抗体产生的阳性率,并进一步分析其与血型、性别、输血次数的关系。结果 5 745名输血患者中,血小板抗体阳性患者108名,总阳性率约1.87%。血小板抗体阳性血型无明显相关性,与性别有相关性,女性阳性率明显比男性高,此外与输血次数呈正比。结论输血等免疫因素刺激导致产生血小板抗体,输血次数越多,血小板抗体产生的概率越大,对于需反复多次输血治疗患者进行血小板抗体筛检,抗体阳性患者给予配型血小板输注治疗,从而能更好的提高血小板输注效率,保证临床治疗效果。
[Abstract]:Objective to investigate the relationship between blood type, sex, blood transfusion frequency and platelet antibody positive rate.Methods from January 1, 2016 to December 31, 2016, 5745 patients with blood transfusion were examined by solid phase agglutination method. The positive rate of platelet antibody was counted, and the relationship between platelet antibody and blood type, sex and blood transfusion was analyzed.Results among 5 745 blood transfusion patients, 108 were platelet antibody positive, the total positive rate was about 1.87.There was no significant correlation between platelet antibody positive blood group and sex. The positive rate of platelet antibody in female was significantly higher than that in male, in addition, it was in direct proportion to the number of blood transfusions.Conclusion Blood transfusion and other immunological factors stimulate the production of platelet antibody. The more times of transfusion, the greater the probability of platelet antibody production. The patients who need repeated blood transfusion are screened for platelet antibody.Patients with positive antibody were treated with matching platelet transfusion, which could improve the efficiency of platelet transfusion and ensure the clinical effect.
【作者单位】：浙江大学医学院附属第一医院输血科;
【分类号】：R457.1

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