2015年广东省东莞市细菌耐药性监测结果

发布时间：2018-04-13 19:07

本文选题：耐药性监测 + 抗菌药物　；参考：《中国感染与化疗杂志》2017年03期

【摘要】：目的了解2015年东莞市细菌耐药性监测情况。方法采用纸片扩散法(Kirby-Bauer法)或自动化仪器法对东莞市22所医院的临床分离菌进行药敏试验,参照2015版CLSI标准判定药敏结果,并用WHONET5.6软件统计分析。结果东莞市各医院全年共检出细菌29 665株,其中革兰阳性菌9 509株,占32.1%,革兰阴性菌20 156株,占67.9%。MRSA和MRCNS分别占金黄色葡萄球菌和凝固酶阴性葡萄球菌(CNS)的23.3%(705/3 024)和43.6%(1 054/2 419),未发现耐万古霉素葡萄球菌;大肠埃希菌和肺炎克雷伯菌产ESBL菌株的检出率分别为36.4%(2 554/7 020)和24.5%(792/3 227),耐碳青霉烯类肠杆菌科细菌(CRE)的检出率为0.2%(30/13 077);耐碳青霉烯类铜绿假单胞菌和鲍曼不动杆菌(CRPA和CRAB)的检出率分别为16.0%(500/3 116)和53.9%(827/1 533)。青霉素耐药肺炎链球菌(PRSP)检出率为10.1%(142/1 404),流感嗜血杆菌产β内酰胺酶率为30.6%(276/902),耐万古霉素的肠球菌(VRE)检出率为0.7%(10/1 441)。结论定期进行细菌耐药性监测有助于了解本地区细菌耐药性变迁,为临床合理规范使用抗菌药物提供依据,指导院感管理防控措施的制定和避免耐药菌株的传播流行。
[Abstract]:Dongguan city in 2015. Objective to investigate the bacterial resistance monitoring method using disk diffusion method (Kirby-Bauer method) susceptibility testing of clinical isolates or automatic instrument method in 22 hospitals in Dongguan City, according to the 2015 edition of the CLSI standard to determine the results of drug sensitivity, and using WHONET5.6 software for statistical analysis. Results the hospitals in Dongguan city were detected 29665 strains of bacteria, 9509 strains of Gram-positive bacteria, accounting for 32.1%, 20156 strains of gram negative bacteria, accounting for 67.9%.MRSA and MRCNS respectively, Staphylococcus aureus and coagulase negative staphylococcus (CNS) 23.3% (705/3 024) and 43.6% (1 054/2 419), found no vancomycin resistant Staphylococcus aureus; Escherichia coli Klebsiella pneumoniae and ESBL producing strains were detected in 36.4% (2 554/7 020) and 24.5% (792/3 227), carbapenem resistant Enterobacteriaceae (CRE) detection rate was 0.2% (30/13 077); carbapenem resistant Pseudomonas aeruginosa Gingivalis and Bauman Acinetobacter (CRPA and CRAB) the detection rate was 16% (500/3 116) and 53.9% (827/1 533). Penicillin resistant Streptococcus pneumoniae (PRSP) detection rate was 10.1% (142/1 404), Haemophilus influenzae ESBLs producing rate was 30.6% (276/902), vancomycin resistant Enterococcus the detection rate was 0.7% (VRE) (10/1 441). Conclusion the regular surveillance of bacterial resistance is helpful to understand the changes of the local bacterial resistance, provide the basis for clinical rational use of antimicrobial agents to develop and guide the management of nosocomial infection prevention and control measures to avoid the spread of drug resistant strains.

【作者单位】：广东省东莞市中山大学附属东华医院检验科;
【分类号】：R446.5

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