呼吸功能锻炼对老年腹部手术患者术后肺部感染及免疫功能的影响

发布时间：2018-04-14 12:04

  本文选题：腹部手术 + 呼吸功能锻炼　； 参考：《中华医院感染学杂志》2017年19期

【摘要】：目的探讨呼吸功能锻炼在老年腹部手术患者中的临床应用价值。方法选取2014年1月-2015年12月于医院行腹部手术的100例老年患者作为临床研究对象,随机分为研究组和对照组,各50例。对照组老年腹部手术患者采用手术常规护理干预,研究组老年腹部手术患者则在对照组常规护理基础之上给予呼吸功能锻炼的强化干预,并分别比较和分析两组患者的肺部感染发生情况,肺功能变化情况,免疫细胞因子变化情况,T细胞亚群变化情况。结果研究组患者肺部感染率为6.00%显著低于对照组20.00%(P0.05);治疗后研究组患者用力肺活量(FVC)(3.15±0.18)L,第1秒用力呼气容积率(FEV1)(2.80±0.51)L,最大呼气流量(PEF)(4.89±0.90)L/S较对照组(2.84±0.21)L,(2.35±0.45)L和(4.15±0.83)L/S明显提高;治疗后研究组患者免疫细胞因子白细胞介素-6(IL-6)为(203.17±35.37)ng/L,IL-8(27.16±2.04)ng/L,肿瘤坏死因子-α(TNF-α)(13.02±1.15)ng/L较对照组(260.84±37.53)ng/L,(32.57±2.81)ng/L和(19.34±1.62)ng/L明显降低;治疗后研究组患者T细胞亚群CD4~+(40.74±5.02)%,CD4~+/CD8~+(1.54±0.32)较对照组CD4~+(29.50±4.13)%,CD4~+/CD8~+(1.04±0.21)明显提高,而CD8~+(25.42±4.10)%较对照组CD8~+(28.35±4.42)%明显降低;差异均具有显著性意义(P均0.05)。结论呼吸功能锻炼对于改善老年腹部手术患者肺功能,降低肺部感染率及提高免疫功能均具有十分重要的临床意义。
[Abstract]:Objective to explore the clinical value of respiratory function exercise in elderly patients undergoing abdominal surgery.Methods 100 elderly patients undergoing abdominal surgery from January 2014 to December 2015 were randomly divided into study group and control group (50 cases each).The elderly patients in the control group were treated with routine nursing intervention, while the elderly patients in the study group were given intensive intervention of respiratory function exercise on the basis of routine nursing in the control group.The incidence of pulmonary infection, the changes of pulmonary function, and the changes of immune cytokines were compared and analyzed in the two groups.Results the pulmonary infection rate in the study group was significantly lower than that in the control group (P 0.05), the forced vital capacity of the study group was 3.15 卤0.18 L, the forced expiratory volume in the first second was 2.80 卤0.51L, the maximal expiratory flow rate was 4.89 卤4.89 卤0.90)L/S, and that in the control group was 2.84 卤0.21 L, 2.35 卤0.45 and 4.15 卤0.83)L/S, respectively.娌荤枟鍚庣爺绌剁粍鎮ｈ，

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