三亚某医院血流感染病原菌分布及耐药性

发布时间：2018-04-15 01:35

本文选题：血流感染 + 血培养　；参考：《中国感染控制杂志》2017年03期

【摘要】：目的了解三亚地区某医院血流感染病原菌分布及其耐药情况。方法回顾性分析该院2013年1月—2015年12月临床送检血培养标本及药敏试验结果。结果 3 195份血培养标本共检出阳性病原菌356株,阳性率为11.14%,其中革兰阴性菌215株(占60.39%),革兰阳性菌122株(占34.27%),真菌19株(占5.34%)。革兰阴性菌分离菌株数较多的是大肠埃希菌(90株,25.28%)、肺炎克雷伯菌(60株,16.85%)及假鼻疽伯克霍尔德菌(24株,6.74%);革兰阳性菌则以金黄色葡萄球菌(42株,11.80%)、凝固酶阴性葡萄球菌(38株,10.67%)及链球菌属细菌(33株,9.27%)居多。大肠埃希菌及肺炎克雷伯菌对头孢哌酮/舒巴坦、阿米卡星及碳青霉烯类耐药率低于10.00%。假鼻疽伯克霍尔德菌对多数抗菌药物的耐药率低于10.00%。主要革兰阳性菌未检测出耐利奈唑胺及万古霉素的菌株。结论近期该院血流感染病原菌以革兰阴性菌为主,尤其假鼻疽伯克霍尔德菌的分离率较其他地区高,应引起临床重视。
[Abstract]:Objective to investigate the distribution and drug resistance of pathogenic bacteria of blood stream infection in a hospital in Sanya area.Methods the results of clinical blood culture and drug sensitivity test from January 2013 to December 2015 were analyzed retrospectively.Results 356 strains of pathogenic bacteria were detected in 3 195 blood samples, the positive rate was 11.14%, among which 215 strains were Gram-negative bacteria (60.39%), 122 strains were Gram-positive bacteria (34.27%), 19 strains were fungi (5.34%).Gram-negative bacteria isolated were Escherichia coli 90 strains 25.28%, Klebsiella pneumoniae 60 strains 16.85) and Bacillus pseudorrhoeae 24 strains 6.740.Gram-positive bacteria consisted of 42 strains of Staphylococcus aureus 11.80% and coagulase-negative staphylococcus.And 33 strains of Streptococcus spp.The resistance rates of Escherichia coli and Klebsiella pneumoniae to cefoperazone / sulbactam, amikacin and carbapenes were lower than 10.00.The resistance to most antimicrobial agents was lower than 10.00.The main gram-positive strains were not resistant to linazolamine and vancomycin.Conclusion Gram-negative bacteria are the main pathogens of blood flow infection in this hospital recently, especially the isolation rate of Burkholderia pseudorhini is higher than that in other areas, which should be paid more attention to in clinic.
【作者单位】：海南省第三人民医院;海南医学院;中南大学湘雅三医院医学实验中心;
【基金】：海南省三亚市医疗卫生科技创新基金资助项目(2014YW23)
【分类号】：R197.323;R446.5

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