黏液型铜绿假单胞菌临床分布与耐药性分析

发布时间：2018-04-15 11:39

本文选题：黏液型铜绿假单胞菌 + 临床分布　；参考：《中华医院感染学杂志》2017年12期

【摘要】：目的为临床合理使用抗菌药物治疗黏液型铜绿假单胞菌感染提供必要的病原学依据。方法收集医院2012年1月-2016年12月临床分离的86株黏液型铜绿假单胞菌感染病例,通过查阅病历获得患者一般资料、疾病情况、抗菌药物使用等信息,回顾性分析黏液型铜绿假单胞菌的临床分布、耐药性及疗效。结果临床送检标本共分离出黏液型铜绿假单胞菌86株,男性占72.09%,女性占27.01%;老年人占83.72%,中年人占12.79%,青年人占3.49%;肺部感染、泌尿系感染和创伤感染分别占93.02%、3.49%和3.49%;氨苄西林/舒巴坦和磺胺甲VA唑/甲氧苄啶的耐药率为98.84%、95.35%,替卡西林和替卡西林/克拉维酸的耐药率为22.09%、13.95%,哌拉西林和哌拉西林/他唑巴坦的耐药率为11.63%和10.47%;疗效显著的病例占83.72%。结论黏液型铜绿假单胞菌感染主要集中在老年男性的呼吸道感染,临床应根据药敏结果合理选用抗菌药物。
[Abstract]:Objective to provide necessary etiological evidence for the rational use of antimicrobial agents in the treatment of myxomonas aeruginosa infection.Methods 86 clinical isolates of Pseudomonas aeruginosa from January 2012 to December 2016 were collected, and the general information of patients, the condition of disease and the use of antimicrobial agents were obtained by consulting the medical records.The clinical distribution, drug resistance and efficacy of mucinous Pseudomonas aeruginosa were analyzed retrospectively.Results A total of 86 strains of Pseudomonas aeruginosa were isolated from clinical samples, including 72.09 males and 27.01 females, 83.72% of the elderly, 12.79% of the middle-aged, 3.49% of the young, pulmonary infection.Urinary tract infection and trauma infection accounted for 93.02% and 3.49% respectively, ampicillin / sulbactam and sulfamethoxazole / trimethoprim were 98.84 and 95.355.The resistant rates of tekassim and ticacillin / clavulanic acid were 22.0913.95, piperacillin and piperacillin were higher than those of ampicillin / sulbactam and sulfamethoxazole / trimethoprim.The drug resistance rate of tazobactam was 11.63% and 10.47%, and 83.72% of the patients had significant curative effect.Conclusion Myxomonas aeruginosa infection is mainly concentrated in the respiratory tract infection of the aged men, and antibiotics should be selected reasonably according to the results of drug sensitivity.
【作者单位】：重庆医科大学附属大学城医院检验科;
【分类号】：R446.5

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