双能CT虚拟平扫技术在胰腺癌中的应用评估

发布时间：2018-04-21 03:27

本文选题：胰腺癌 + 体层摄影术　；参考：《临床放射学杂志》2017年09期

【摘要】：目的探讨双能CT虚拟平扫(VNC)技术在胰腺癌评估中替代常规真实平扫(TNC)的可行性及临床价值。方法搜集经手术病理证实的33例胰腺腺癌患者的病例资料。所有患者均行双能CT平扫和双期增强扫描,增强图像经双能软件处理得到VNC图及碘分布图(碘图)。比较TNC、动脉期虚拟平扫(AVNC)、实质期虚拟平扫(VVNC)三组图像中胰腺癌组织的CT值、标准差值(SD)、信号噪声比(SNR);比较三组图像主观质量评分以及对胰腺癌的检出敏感性差异。结果胰腺癌组织AVNC及VVNC的CT值与TNC的CT值呈正相关(动脉期r=0.793,实质期r=0.555);TNC、AVNC和VVNC三组图像中胰腺癌组织的CT值由大到小依次为TNC、AVNC、VVNC,SD值由大到小依次为TNC、VVNC、AVNC,SNR值由大到小依次为AVNC、VVNC、TNC,分别两两比较三组病灶的CT值、SD及SNR值,三者TNC与AVNC及VVNC之间均有统计学差异(P0.05),AVNC与VVNC之间无统计学差异(P0.05);三组图像质量均满足临床诊断要求,主观质量评分无统计学差异(P0.05);三组图像对胰腺癌检出敏感性差异无统计学意义(P0.05)。结论双能CT所得VNC图像质量完全能满足诊断要求,可以代替以往动态增强扫描中作为基线的常规平扫,碘图具有额外的价值。
[Abstract]:Objective to evaluate the feasibility and clinical value of dual energy CT virtual plain scan (VNC-) in the evaluation of pancreatic cancer. Methods 33 cases of pancreatic adenocarcinoma confirmed by operation and pathology were collected. All patients underwent dual energy CT plain scan and dual phase enhanced scan. Enhanced images were processed by dual energy software to obtain VNC and iodine distribution (iodide). To compare the CT value, standard difference value and signal noise ratio of pancreatic carcinoma in TNC, virtual plain scan AVNCscan in arterial phase and VVNCin in parenchymal phase, and to compare the subjective quality score and sensitivity of the three groups in detecting pancreatic carcinoma. Results the CT values of AVNC and VVNC in pancreatic carcinoma were positively correlated with those of TNC (arterial phase: 0.793, parenchymal phase: rr: 0.555A). The CT values of pancreatic cancer tissues were from large to small, from large to small, from large to small, from large to small. The CT value and SNR value of the lesions were compared in two groups for AVNCU and VVNCU TNC, and the CT values of SD and SNR were compared in two groups. There was no statistical difference between TNC and AVNC and VVNC in the three groups, and the quality of the three groups could meet the requirements of clinical diagnosis. There was no statistical difference in subjective quality score (P 0.05) and there was no significant difference in the sensitivity of the three groups to the detection of pancreatic cancer (P 0.05). Conclusion the quality of VNC images obtained by dual-energy CT can completely meet the diagnostic requirements and can replace the conventional plain scan which is used as the baseline in the previous dynamic contrast-enhanced scanning. The iodine image has additional value.
【作者单位】：浙江大学医学院附属第二医院放射科;浙江省立同德医院放射科;
【基金】：浙江省医药卫生科技计划项目(编号:2012KYB047)
【分类号】：R730.44;R735.9

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