孤立性纤维性肿瘤影像学表现及与Ki-67表达的相关性

发布时间：2018-04-30 10:47

本文选题：孤立性纤维性肿瘤 + 体层摄影术　；参考：《安徽医科大学学报》2017年05期

【摘要】：探讨孤立性纤维性肿瘤影像学表现及与Ki-67表达的相关性。收集经病理证实的27例孤立性纤维性肿瘤患者CT、MRI资料,分析其影像学特征,其中17例经免疫组化检查测定Ki-67,计算该17例患者CT动脉期最大强化率(p CER),结果进行统计学分析。所有病例中发生于胸部17例,腹部5例,颅脑1例,颌面部4例。23例行CT检查,4例行MRI检查。病灶表现为边界清楚的软组织肿块,CT平扫密度均匀或不均匀,MRI检查T1WI以等低信号为主、T2WI信号混杂多样,增强扫描可见强化。测定Ki-67的17例CT增强病例中,p CER与Ki-67表达呈正相关性(rs=0.828,P0.01),p CER值越高,其Ki-67表达越高。孤立性纤维性肿瘤可发生于全身多个部位,影像学表现可以一定程度反映肿瘤生物学行为。
[Abstract]:To investigate the imaging features of solitary fibrous tumors and its correlation with Ki-67 expression. Ct MRI data of 27 patients with solitary fibrous tumor confirmed by pathology were collected and their imaging features were analyzed. Ki-67 was measured by immunohistochemical examination in 17 patients. The maximum enhancement rate of CT arterial phase was calculated in 17 patients and the results were statistically analyzed. All the cases occurred in 17 cases of chest, 5 cases of abdomen, 1 case of craniocerebral, 4 cases of maxillofacial. 23 cases of CT and 4 cases of MRI. The lesions were characterized by homogeneous or non-homogeneous T1WI with homogeneous or uneven density on plain CT scan with clear margin. The signal intensity of T2WI was mixed and varied, and enhancement was observed on enhanced CT scan. There was a positive correlation between the expression of Ki-67 and the expression of Ki-67 in 17 cases of Ki-67. The higher the value of CER was, the higher the expression of Ki-67 was. Solitary fibrous tumors can occur in many parts of the body, and imaging findings can reflect the biological behavior of tumors to some extent.
【作者单位】：安徽医科大学第一附属医院放射科;安徽医科大学第一附属医院病理科;
【基金】：安徽高校自然科学研究项目(编号:KJ2015A072)
【分类号】：R730.44;R445.2

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