消化道肿瘤化疗病人营养状况与生活质量的纵向研究

发布时间：2018-05-01 17:38

本文选题：消化道肿瘤 + 化疗　；参考：《护理研究》2017年02期

【摘要】：[目的]调查消化道肿瘤化疗病人营养状况、生活质量在6个化疗周期中的变化趋势及相互关系。[方法]选取2013年10月—2014年8月南京市某三级甲等医院肿瘤科入院行初次化疗的73例消化道肿瘤病人作为研究对象。病人入院24h内及每个化疗周期采用改良版病人主观全面评价量表(abPG-SGA)进行营养评价,采用欧洲疾病研究与治疗组织生活质量测定量表(EORTC QLQ-C30)评定病人生活质量。[结果]6个化疗周期中病人营养不良发生率由50.79%上升至69.84%。辅助化疗病人的社会功能随化疗周期的延长呈现逐渐下降趋势,姑息化疗病人的躯体功能、角色功能、情绪功能、社会功能及总体健康状况随化疗周期的延长呈现逐渐下降趋势,化疗病人疲乏、恶心呕吐、食欲丧失及经济困难随化疗周期的延长呈现逐渐加重趋势。6个化疗周期中,病人营养评分与生活质量中的躯体功能、角色功能、情绪功能、认知功能、总体健康状况均呈负相关(P0.05)。病人营养评分与生活质量中的疲乏、恶心呕吐、食欲丧失均呈正相关(P0.05)。[结论]消化道肿瘤病人化疗期间随着营养状况的下降,生活质量变差。提示医护人员应及时对消化道肿瘤化疗病人的营养状况进行评估,合理进行营养干预,从而提高病人生活质量。
[Abstract]:[objective] to investigate the nutritional status, quality of life (QOL) of patients with digestive tract neoplasms treated with chemotherapy in 6 cycles. [methods] from October 2013 to August 2014, 73 patients with digestive tract tumors who were admitted to the Department of Oncology of Grade 3A Hospital in Nanjing were selected as the study objects. Within 24 hours of admission and every chemotherapy cycle, the patients were evaluated with the modified subjective comprehensive evaluation scale (ABPG-SGA), and the quality of life (QQC30) was evaluated with the European Organization for Disease Research and treatment (EORTC QLQ-C30). [results] the incidence of malnutrition increased from 50.79% to 69.84% in 6 chemotherapy cycles. The social function of adjuvant chemotherapy patients decreased gradually with the prolongation of chemotherapy cycle, and the somatic function, role function, emotional function of palliative chemotherapy patients, The social function and overall health status decreased with the prolongation of chemotherapy cycle, and the fatigue, nausea and vomiting, loss of appetite and economic difficulties of chemotherapy patients gradually increased with the prolongation of chemotherapy cycle. There was a negative correlation between nutritional score and body function, role function, emotional function, cognitive function and overall health status of patients with quality of life (P 0.05). There was a positive correlation between nutritional score and fatigue, nausea, vomiting and loss of appetite in patients with quality of life (P 0.05). [conclusion] the quality of life of patients with digestive tract tumor decreased with the decrease of nutritional status during chemotherapy. It is suggested that the medical staff should evaluate the nutritional status of the patients with digestive tract tumor chemotherapy in time and carry out nutrition intervention reasonably to improve the quality of life of the patients.
【作者单位】：江苏建康职业学院;南京医科大学护理学院;南京医科大学第一附属医院;南京市安宁医院;
【基金】：江苏省一级学科重点学科护理学开放基金项目,编号:NYHL201402
【分类号】：R473.73

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