输注两种不同红细胞对自身免疫性溶血性贫血患者实验室指标及疗效影响的对比

发布时间：2018-05-04 23:44

本文选题：自身免疫性溶血性贫血 + 输血治疗　；参考：《中国实验血液学杂志》2017年03期

【摘要】：目的:探究输注2种不同红细胞对自身免疫性溶血性贫血(AIHA)患者实验室指标及疗效的影响。方法:采用回顾性探究的方法,选取2015年6月至2016年6月本院收治的自身免疫性溶血性贫血患者120例,其中60例患者输血治疗采用输注洗涤红细胞治疗,为甲组;另60例患者输血治疗采用输注去白红细胞治疗,为乙组。查询并记录比较甲组和乙组患者输血治疗前和输血后24 h的实验室指标变化情况,对比2组患者的疗效、症状改善情况和不良反应发生情况。结果:2组患者治疗1 d后的RBC、Hb水平较输血治疗前非常显著升高(P0.01),TBIL、Ret水平较输血治疗前非常显著降低(P0.001)。2组患者治疗前及治疗后的RBC、Hb、TBIL、Ret水平,治疗后乏力、头晕、气短、心悸等贫血症状改善情况,治疗后综合疗效,不良反应发生率等的差异均无统计学意义(P0.05)。结论:去白红细胞及洗涤红细胞均能在短时间内明显缓解AIHA患者的贫血情况。
[Abstract]:Objective: to investigate the effects of two different kinds of red blood cells on laboratory indexes and efficacy in patients with autoimmune hemolytic anemia (AHA). Methods: 120 patients with autoimmune hemolytic anemia treated in our hospital from June 2015 to June 2016 were selected by retrospective study. Among them, 60 patients were treated by transfusion of washed red blood cells. The other 60 patients were treated by transfusion of white red blood cells, B group. To investigate and record the changes of laboratory indexes before and 24 hours after blood transfusion in group A and group B, to compare the curative effect, symptom improvement and adverse reaction of the two groups. Results the level of RBCnTBILHb in two groups was significantly higher than that before blood transfusion. The level of TBILRet was significantly lower than that before and after blood transfusion in group 2. The level of TBILRet in group B was significantly lower than that in group B before and after blood transfusion. After treatment, there was fatigue, dizziness, and shortness of breath in group B, and the level of TBILRet in group B was significantly lower than that in group B before and after blood transfusion. There was no significant difference in symptoms of palpitation, comprehensive curative effect and incidence of adverse reactions after treatment (P 0.05). Conclusion: albino red blood cells and washed red blood cells can alleviate anemia in patients with AIHA in a short time.
【作者单位】：福建省泉州市第一医院输血科;福建省泉州市第一医院血液科;
【分类号】：R457.1;R556.62

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