超声评价2型糖尿病患者合并非酒精性脂肪肝及与心脏瓣膜钙化的相关性研究

发布时间：2018-05-08 22:10

本文选题：超声 + 糖尿病　；参考：《中国现代医学杂志》2017年11期

【摘要】：目的探讨2型糖尿病(T2DM)患者合并非酒精性脂肪肝(NAFLD)及与心脏瓣膜钙化(HVC)的相关性。方法 150例T2DM患者,依据病程分为两组,病程10年(A组)75例,病程≤10年(B组)75例,同时选取75例健康志愿者作为对照组(C组)。对3组患者行肝脏超声及经胸超声心动图检查,根据二维图像特征将NAFLD分为轻度、中度及重度,获取HVC评分,并进行相关性分析。结果 A、B两组间NAFLD和HVC的阳性率及严重程度均高于C组,且A组高于B组,差异有统计学意义(P0.05)。病程与NAFLD及HVC均呈正相关关系(r=0.449和0.338,P0.05),且NAFLD和HVC存在正相关关系(r=0.233,P0.05)。结论随着T2DM患者的病程增加,NAFLD和HVC的程度加重,超声技术可以客观地评价T2DM患者合并的这两种异常改变,具有重要的临床意义。
[Abstract]:Objective to investigate the relationship between NAFLDD and cardiac valve calcification (HVC) in patients with type 2 diabetes mellitus (T2DM) complicated with nonalcoholic fatty liver. Methods one hundred and fifty patients with T2DM were divided into two groups according to the course of disease. 75 patients in group A and 75 patients in group B were divided into two groups according to the course of disease. 75 healthy volunteers were selected as control group. Three groups of patients were examined by liver ultrasound and transthoracic echocardiography. According to the characteristics of two-dimensional images, NAFLD was divided into mild, moderate and severe. The HVC score was obtained and the correlation analysis was carried out. Results the positive rate and severity of NAFLD and HVC in group A were higher than those in group C and group A were higher than group B (P 0.05). The course of disease was positively correlated with NAFLD and HVC, and there was a positive correlation between NAFLD and HVC. Conclusion with the increase of the course of disease in T2DM patients, the degree of NAFLD and HVC is aggravated. Ultrasound can objectively evaluate the two abnormal changes in T2DM patients, which is of great clinical significance.
【作者单位】：大连医科大学附属第二医院超声科;大连医科大学附属第二医院内分泌科;
【分类号】：R445.1;R575.5;R587.1

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