健康成年人肾脏DKI的可行性及可重复性研究

发布时间：2018-05-09 04:33

本文选题：扩散峰度成像 + 肾脏　；参考：《中国医学计算机成像杂志》2017年03期

【摘要】：目的:探讨正常志愿者肾脏扩散峰度成像(DKI)的可行性和重复性。方法:30名健康志愿者纳入本研究,采用西门子3.0T磁共振行两次DKI扫描,分别测量两侧肾脏的上、中、下三个位置的平均扩散系数(MD)和平均峰度系数(MK),采用配对t检验和单因素方差分析比较差异是否统计学意义;采用Bland-Altman法对两次扫描的参数进行重复性评价。结果:测量者两次测量获得的MD和MK具有很好的一致性(ICC为0.755~0.940);两次扫描、两侧肾脏不同测量部位MD和MK值比较均不具有统计学意义(P0.05);两次扫描,右肾下部的MD值和MK值重复性较好(分别为0.00±0.21和0.000±0.04)。结论:肾脏DKI具有可行性和重复性,尤以右肾下部的重复性较好。
[Abstract]:Objective: to investigate the feasibility and reproducibility of DKI in normal volunteers. Methods Twenty healthy volunteers were enrolled in the study. Siemens 3.0T magnetic resonance imaging was used to perform two DKI scans. The upper and middle kidneys of both sides were measured respectively. The average diffusion coefficient (MDM) and the mean kurtosis coefficient (MK) of the next three positions were compared by paired t test and single factor ANOVA, and the repeatability of the two scanning parameters was evaluated by Bland-Altman method. Results: there was good consistency between MD and MK obtained by two measurements. The ICC was 0.755 ~ 0.940, and there was no significant difference in MD and MK values between the two kidneys in two scans, and there was no significant difference in MD and MK values between the two sides of the kidney. The reproducibility of MD value and MK value in the lower part of the right kidney were better (0.00 卤0.21 and 0.000 卤0.04), respectively. Conclusion: renal DKI is feasible and reproducible, especially in the lower right kidney.
【作者单位】：潍坊市益都中心医院CT-MR科;
【分类号】：R445.2;R69

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