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某院住院患者肺炎链球菌感染与耐药性研究

发布时间:2018-05-09 08:01

  本文选题:肺炎链球菌 + 耐药 ; 参考:《中华医院感染学杂志》2017年13期


【摘要】:目的探讨医院肺炎链球菌感染与耐药性情况,为临床治疗提供指导依据。方法选取2015年1月-2016年12月于医院住院或就诊的感染者标本8126份,进行病原菌菌株鉴定和药敏试验;由专职人员统计标本采集科室、部位及患者年龄、性别等基本信息。结果 8126份患者标本,分离得到肺炎链球菌158份,检出率为1.94%。共检出病原菌158株,其中痰液检出125株占79.11%,血液检出12株占7.59%,胸水检出8株占5.06%、脑脊液检出6株占3.80%、脓液检出4株占2.53%,其他标本检出3株占1.90%;≤3岁患者检出86株占54.43%,4~15岁患者检出12株占7.59%,16~40岁患者检出14株占8.86%,41~60岁患者检出18株占11.39%,61岁以上患者检出28株占17.72%;儿科检出92株,占58.23%,重症监护室检出26株占16.46%,呼吸科检出22株占13.92%,肿瘤科检出10株占6.33%,其他科室检出8株占5.06%;2015年检出69株占43.67%,2016年检出89株占56.33%。2015年-2016年肺炎链球菌耐药率有上升趋势;肺炎链球菌对青霉素G、红霉素、克林霉素和四环素耐药率均在80%以上,对氯霉素、万古霉素、利奈唑胺、左氧氟沙星、阿米卡星、头孢唑林和头孢噻肟等耐药率较低,较为敏感。结论婴幼儿是肺炎链球菌感染的高危人群,且肺炎链球菌耐药率呈上升趋势。
[Abstract]:Objective to explore the situation of nosocomial streptococcus pneumoniae infection and drug resistance in order to provide guidance for clinical treatment. Methods from January 2015 to December 2016, 8126 infected specimens were selected for identification of pathogenic strains and drug susceptibility tests, and basic information such as department, location, patient age, sex and so on were collected by professional staff. Results among 8126 specimens, 158 strains of Streptococcus pneumoniae were isolated and the detection rate was 1.94%. 158 strains of pathogenic bacteria were detected. Among them, 125 strains were detected in sputum, 12 in blood, 5.06 in pleural fluid, 6 in cerebrospinal fluid, 2.53 in pus, 3 in other specimens, 86 in patients with 鈮,

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