健康管理人群缺血性异常心电图的影响因素

发布时间：2018-05-10 21:15

本文选题：缺血性异常心电图 + 影响因素　；参考：《山东大学学报(医学版)》2017年06期

【摘要】：目的阐明健康管理人群的缺血性异常心电图的影响因素及非缺血性异常心电图对重要的缺血性异常心电图的预测价值。方法选择山东多中心健康管理纵向观察队列中至少参加2次体检的个体,排除冠心病及缺血性异常心电图患者,构建随访队列。对随访中发生缺血性异常心电图者与未发生缺血性异常心电图者,比较其基线信息,并筛选影响缺血性异常心电图的危险因素,进一步构建缺血性异常心电图的Cox回归分析模型。结果队列中共纳入45 546例,随访时间1~7年,平均3.24年,随访中共有7 656例出现缺血性异常心电图,发病密度为77.57/1 000人年。缺血性异常心电图发生的主要影响因素是年龄偏高、女性、高收缩压和舒张压、高空腹血糖、白细胞计数高以及非缺血性异常心电图R波高电压。结论本研究探讨导致缺血性异常心电图的危险因素,为制定切实可行的健康干预措施提供了科学依据。
[Abstract]:Objective to elucidate the influencing factors of ischemic abnormal electrocardiogram (ECG) and the predictive value of nonischemic abnormal ECG in health management population. Methods the patients with coronary heart disease (CHD) and ischemic abnormal electrocardiogram (ECG) were selected from the longitudinal observation cohort of multi-center health management in Shandong province for at least two physical examinations and the follow-up cohort was constructed. The baseline information of ischemic abnormal electrocardiogram was compared with that of non-ischemic abnormal electrocardiogram, and the risk factors of ischemic abnormal electrocardiogram were screened. The Cox regression model of ischemic abnormal electrocardiogram was further constructed. Results A total of 45 546 patients were enrolled in the cohort, followed up for 1 ~ 7 years (mean 3.24 years). A total of 7 656 cases were followed up with abnormal ischemic electrocardiogram (ECG), and the incidence density was 77.57 / 1 000 person-years. The main influencing factors of ischemic abnormal electrocardiogram were high age, female, high systolic and diastolic blood pressure, high fasting blood glucose, high white blood cell count and high voltage of R wave in non-ischemic abnormal ECG. Conclusion to explore the risk factors of ischemic abnormal electrocardiogram, this study provides scientific basis for making feasible health intervention measures.
【作者单位】：山东大学附属省立医院心内科;山东大学附属省立医院健康查体中心;山东大学公共卫生学院生物统计学系;山东大学齐鲁生物医学大数据研究中心;山东电力中心医院心内科;
【基金】：国家自然科学基金(81273177) 山东省医药卫生科技发展计划项目(2013WS0230)
【分类号】：R540.41

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