能谱CT预测肝癌TACE术后碘油沉积情况的初步研究

发布时间：2018-05-16 00:26

本文选题：能谱CT + 原发性肝癌　；参考：《临床放射学杂志》2017年07期

【摘要】：目的探讨能谱CT物质定量分析与肝癌TACE术后碘油沉积情况的相关性及其临床价值。方法对28例原发性肝癌患者TACE术前进行能谱CT扫描,术后1个月CT复查。利用能谱分析软件(GSI)对术前能谱图像进行后处理,用混合能量和单能量图像对病灶进行观察,分别记录动脉期、静脉期肿瘤病灶碘基值及对比术后复查图像病灶碘油沉积区域和无碘油沉积区域术前碘基值、腹主动脉和门静脉碘基值。结果术后仅1例病灶碘油完全沉积。术后碘油沉积面积50%病灶的术前动脉期标准化碘浓度(ANIC)较术后碘油沉积面积50%的病灶高,分别为0.25±0.04、0.18±0.06(P0.01),标准化碘浓度比率(ICratio)及静脉期标准化碘浓度(VNIC)差异无统计学意义。同一病灶碘油沉积区域动脉期标准化碘浓度(ANIC)较无碘油沉积区域高,分别为0.21±0.05、0.16±0.06(P0.01)。结论利用能谱CT测得的动脉期标准化碘基值可以较好的预测TACE术后肝癌病灶碘油沉积情况,从而对评价肝癌预后及为TACE术筛选合适病例提供一定参考。
[Abstract]:Objective to investigate the correlation between quantitative analysis of energy dispersive CT materials and lipiodol deposition after TACE and its clinical value. Methods 28 patients with primary liver cancer were examined by energy dispersive CT before TACE and 1 month after operation. Energy spectrum analysis software (GSI) was used to post-process the preoperative energy spectrum images. The lesions were observed with mixed energy and single energy images. The arterial phase was recorded respectively. The iodine base value of the tumor focus in venous phase and the iodine base value before operation and abdominal aorta and portal vein iodine base value in the focus of lipiodol deposition and no lipiodol deposition were compared. Results only 1 case had complete deposition of lipiodol. The preoperative arterial standardized iodine concentration (ANICI) of 50% lipiodol depositional area was higher than that of 50% of postoperative lipiodol deposition area (0.25 卤0.04 卤0.18 卤0.06 P0.01C). There was no significant difference in the standardized iodine concentration ratio (ICratioI) and the venous phase standardized iodine concentration (VNICs). The standardized iodine concentration (ANIC) in the arterial phase of lipiodol deposition area in the same lesion was higher than that in the non-lipiodol depositional area, which was 0.21 卤0.05 卤0.16 卤0.06 (P 0.01), respectively. Conclusion the standardized iodine base value of arterial phase measured by EDS can be used to predict the lipiodol deposition of hepatocellular carcinoma after TACE, which provides a reference for evaluating the prognosis of HCC and screening suitable cases for TACE.
【作者单位】：上海交通大学医学院附属仁济医院肿瘤介入科;
【基金】：中国肝炎防治基金会王宝恩肝纤维化研究基金资助项目(编号:CFHPC20151013)
【分类号】：R730.44;R735.7

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