2011—2015年临床分离粪肠球菌和屎肠球菌分布情况及耐药性分析

发布时间：2018-05-16 19:01

本文选题：粪肠球菌 + 屎肠球菌　；参考：《南京医科大学学报(自然科学版)》2017年10期

【摘要】：目的:了解徐州医科大学附属医院2011—2015年粪肠球菌和屎肠球菌的标本来源、科室分布情况及5年间的耐药性变迁。方法:应用梅里埃VITEK2 COMPACT全自动微生物分析系统进行细菌鉴定及抗菌药物敏感试验(MIC法),结果按美国临床实验室标准化研究所标准(2014版)判定,以WHONET5.6软件分析数据。结果:2011—2015年共分离到999株非重复肠球菌属细菌,以粪肠球菌(494株)和屎肠球菌(386株)为主;菌株来源以尿液最多;粪肠球菌和屎肠球菌在重症医学科明显高于其他科室,其次为泌尿外科;屎肠球菌对一些常用抗菌药物的耐药率明显高于粪肠球菌。结论:本院重症医学科、泌尿外科和急诊ICU是预防控制的重点科室;5年间本院粪肠球菌和屎肠球菌耐药率明显高于CHINET水平,耐药形势严峻,需高度警惕,加强耐药监测和规范临床对抗菌药物的使用。
[Abstract]:Objective: to investigate the origin of Enterococcus faecalis and Enterococcus faecium in the affiliated Hospital of Xuzhou Medical University from 2011 to 2015. Methods: the bacterial identification and antimicrobial susceptibility test were carried out by using Merier VITEK2 COMPACT automatic microbiological analysis system. The results were determined according to the standards of American Institute of Clinical Laboratory Standardization, and the data were analyzed by WHONET5.6 software. Results from 2011 to 2015, 999 strains of non-Enterococcus faecalis (494 strains) and 386 strains of Enterococcus faecium were isolated in 2011-2015. The most strains were from urine, and Enterococcus faecalis and Enterococcus faecium were significantly higher than those in other departments of intensive medicine. The resistance rate of Enterococcus faecium to some common antimicrobial agents was significantly higher than that of Enterococcus faecalis. Conclusion: the rate of drug resistance of Enterococcus faecalis and Enterococcus faecium in urology department and emergency department of ICU in our hospital is obviously higher than that of CHINET in 5 years. Strengthen drug resistance monitoring and standardize the clinical use of antimicrobial agents.
【作者单位】：徐州医科大学医学技术学院;徐州医科大学附属医院检验科;
【基金】：江苏省卫生计生委医学科研课题(H201631) 国家自然科学基金(81471994) 江苏省自然科学基金(BK20151154)
【分类号】：R446.5

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