2型糖尿病患者下肢动脉血管回声跟踪技术检测指标与血脂及血糖的相关性

发布时间：2018-05-25 23:35

  本文选题：型糖尿病 + 血管回声跟踪技术　； 参考：《中华实用诊断与治疗杂志》2017年01期

【摘要】：目的应用血管回声跟踪技术检测2型糖尿病患者足背动脉及乆动脉弹性指标,探讨其与血脂及血糖的相关性。方法 2型糖尿病患者40例(观察组),体检健康者40例(对照组),检测2组空腹血糖(fasting plasma glucose,FPG)、糖化血红蛋白(glycosylated hemoglobin,HbA_(1c))、总胆固醇(total cholesterol,TC)、三酰甘油(triacylglycerol,TG)、高密度脂蛋白胆固醇(high density lipoprotein-cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoproteincholesterol,LDL-C)水平;应用血管回声跟踪技术检测2组足背动脉、乆动脉僵硬度(stiffness parameterβ,β)、血管压力应变弹性系数(pressure-strain elasticity coefficient,E_ρ)、顺应性(arterial compliance,AC)、脉搏波传导速度(pulse wave velocityβ,PWVβ);Pearson相关分析2型糖尿病患者足背动脉和乆动脉弹性指标与FPG、HbA_(1c)、TC、TG、HDL-C、LDL-C的相关性。结果观察组FPG[(8.01±1.95)mmol/L]、HbA_(1c)[(8.66±1.64)mmol/L]、TC[(5.28±0.84)mmol/L]、TG[(1.96±0.89)mmol/L]、LDL-C[(3.11±0.65)mmol/L]高于对照组[(5.35±0.62)、(5.19±0.29)、(4.77±0.21)、(1.54±0.11)、(2.82±0.30)mmol/L](P0.05);观察组左、右侧足背动脉β(14.41±5.06,14.68±4.80)、E_ρ[(198.35±72.89)、(199.82±67.24)kPa]、PWVβ[(8.46±1.66)、(8.52±1.51)m/s]高于对照组[(10.99±4.28)、(11.37±4.25);(137.09±52.38)、(141.27±54.82)kPa;(7.05±1.37)、(7.18±1.37)m/s](P0.05),AC值[(0.080±0.030)、(0.082±0.040)mm~2/kPa]低于对照组[(0.104±0.043)、(0.103±0.042)mm~2/kPa](P0.05);观察组乆动脉左、右侧β(14.21±6.08、14.38±5.86)、E_ρ[(200.35±96.12)、(200.60±88.66)kPa]、PWVβ[(8.51±2.00)、(8.37±1.79)m/s]高于对照组[9.85±4.78、10.29±4.20;(122.77±63.00)、(127.15±52.10)kPa;(6.64±1.62)、(6.79±1.79)m/s](P0.05),AC值[(0.30±0.14)、(0.34±0.18)mm~2/kPa]低于对照组[(0.52±0.22)、(0.49±0.20)mm~2/kPa](P0.05);2型糖尿病患者足背动脉、乆动脉弹性指标β、E_ρ、PWVβ与FPG、HbA_(1c)、TC、LDL-C呈正相关,足背动脉AC与FPG、TC呈负相关,乆动脉AC与HbA_(1c)、TC呈负相关。结论 2型糖尿病患者下肢动脉粥样硬化主要与FPG、HbA_(1c)、TC、LDL-C有关,血管回声跟踪技术可快速、无创地检查下肢小动脉弹性,及时发现血管弹性功能受损情况。
[Abstract]:Objective to investigate the relationship between vascular echo tracking and blood lipids and blood glucose in patients with type 2 diabetes mellitus. Methods Forty patients with type 2 diabetes mellitus (observation group) and 40 healthy persons (control group) were examined for fasting plasma glucose GG, glycosylated hemoglobinated hemoglobin, total cholesterol, triacylglycerol TGG, high density lipoprotein cholesterol high density in the two groups of patients with type 2 diabetes mellitus (control group, n = 40), and glycosylated hemoglobinized hemoglobin (HbAG), total cholesterol (TC), triacylglycerol (TG), high density lipoprotein cholesterol (HDL-C) in the two groups. Low density protein cholesterol (LDL-C); Vascular echo tracking technique was used to detect the dorsal foot artery in two groups. Correlation between arterial stiffness and parameter 尾, pressure-strain elasticity coefficiency, compliance with arterial compliance, pulse wave velocity 尾 and pulse wave velocity in patients with type 2 diabetes mellitus 缁撴灉瑙傚療缁凢PG[(8.01卤1.95)mmol/L],HbA_(1c)[(8.66卤1.64)mmol/L],TC[(5.28卤0.84)mmol/L],TG[(1.96卤0.89)mmol/L],LDL-C[(3.11卤0.65)mmol/L]楂樹簬瀵圭収缁刐(5.35卤0.62),(5.19卤0.29),(4.77卤0.21),(1.54卤0.11),(2.82卤0.30)mmol/L](P0.05);瑙傚療缁勫乏,鍙充晶瓒宠儗鍔ㄨ剦尾(14.41卤5.06,14.68卤4.80),E_蟻[(198.35卤72.89),(199.82卤67.24)kPa],PWV尾[(8.46卤1.66),(8.52卤1.51)m/s]楂樹簬瀵圭収缁刐(10.99卤4.28),(11.37卤4.25);(137.09卤52.38),(141.27卤54.82)kPa;(7.05卤1.37),(7.18卤1.37)m/s](P0.05),AC鍊糩(0.080卤0.030),(0.082卤0.040)mm~2/kPa]浣庝簬瀵圭収缁刐(0.104卤0.043),(0.103卤0.042)mm~2/kPa](P0.05);瑙傚療缁勪箚鍔ㄨ剦宸，

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