不孕症女性的生育压力对子宫内膜及内膜下血流的影响

发布时间：2018-05-29 21:58

本文选题：不孕症 + 压力　；参考：《郑州大学》2017年硕士论文

【摘要】：目的运用国际上验证的FPI量表测量不孕症女性的生育压力状况,分析不孕症女性的生育压力与子宫内膜及内膜下血流的相关性,探讨不孕症女性的生育压力对子宫内膜及内膜下血流的影响。为临床工作制定心理干预措施提供了理论依据。方法以2015年10月~2016年8月来郑州大学第一附属医院生殖医学中心门诊初诊的300例不孕症女性作为病例组,抽取在郑州大学第一附属医院体检中心的90例健康女性作为对照组。采用自行设计的不孕不育患者基本情况调查问卷和生育压力量表(Fertility Problem Inventory,FPI)进行横断面调查,采用三维能量多普勒超声(Three-dimensional power Doppler ultrasonography,3D PD-US)在月经周期的第5—11天测量子宫内膜厚度、类型、子宫内膜及内膜下血管化指数(Vascularization index,VI)、血流指数(Flow index,FI)和血管化血流指数(Vascularization-Flow index,VFI)。根据FPI总分将300例不孕症女性平均分成3组(高分组、中分组和低分组),并选取90例健康女性作为对照组。运用t检验、χ2检验、单因素方差分析和Pearson相关分析等统计学方法进行分析,分析不孕症女性生育压力与子宫内膜及内膜下血流的相关性,探讨不孕不育女性生育压力对子宫内膜及内膜下血流的影响。结果1.本研究对符合纳入标准的300例不孕症女性进行问卷调查,并选取90例正常女性作为对照组。t检验和χ2检验结果显示病例组和对照组的年龄,居住地,文化程度,家庭月收入,生育史,检查日期和月经周期没有差异。2.高分组不孕症女性生育压力的总分为(194.88±16.403)分,社会关注(39.47±5.897)分,夫妻关注(38.22±7.418)分,性关注(51.82±6.169),父母角色的需要(36.24±7.351)分和有子女的生活方式(29.12±5.347)分。中分组不孕症女性生育压力的总分为(163.41±12.149)分,社会关注(31.62±5.499)分,夫妻关注(31.38±6.489)分,性关注(46.48±7.089),父母角色的需要(30.78±6.780)分和有子女的生活方式(23.17±5.879)分。低分组不孕症女性生育压力的总分为(137.06±17.738)分,社会关注(24.72±5.861)分,夫妻关注(24.92±6.890)分,性关注(41.25±8.739),父母角色的需要(29.65±6.662)分和有子女的生活方式(16.53±5.120)分。3.四组在子宫内膜厚度、子宫内膜类型、子宫内膜及内膜下的容积,血管化指数和血管化血流指数方面无统计学差异(P0.05)。而子宫内膜和子宫内膜下FI有显着差异(F=32.96,P0.001;F=47.67,P0.001)。其中对照组的子宫内膜及内膜下血流的VI、FI和VFI高于高分组和低分组的VI、FI和VFI,低分组的子宫内膜及内膜下血流的VI、FI和VFI高于高分组和中分组的VI、FI和VFI,中分组的子宫内膜及内膜下血流的VI、FI和VFI高于高分组的VI、FI和VFI。4.Pearson相关分析结果显示,不孕症女性的生育相关压力各个维度与子宫内膜及内膜下FI呈负相关(r=-0.304,P0.001;r=-0.407,P0.001)。结论1.不孕症女性的生育压力较大。2.四组不同生育压力的不孕症女性其子宫内膜厚度、类型、容积和子宫内膜及内膜下的VI、VFI无差异,子宫内膜及内膜下的FI有差异。3.不孕症女性的生育压力与其子宫内膜及内膜下血流FI呈负相关,与其他血流指数不相关。
[Abstract]:Objective To study the relationship between the reproductive pressure of infertile women and the blood flow in the endometrium and the endometrium , and to explore the relationship between the reproductive pressure of infertile women and the blood flow in the endometrium and the endometrium . The total score of female reproductive pressure in infertile women was ( 34.41 卤 12.149 ) , and the relationship between the female reproductive pressure of infertile women and the blood flow in the endometrium and the endometrium was analyzed . The results showed that the total score of female reproductive pressure in infertile women was ( 39.47 卤 5.81 ) , the parents ' role ( 29.65 卤 6.662 ) and the life style of the children ( 16.53 卤 5.347 ) . The VI , FI and VFI of the blood flow in the endometrium and the endometrium of the control group were higher than those of the high and low grouping VI , FI and VFI , the VI , FI and VFI of the lower blood flow were higher than those of the high grouping , the VI , FI and VFI of the lower blood flow were higher than those of the high grouping VI , FI and VFI . 4 . Pearson correlation analysis showed that the various dimensions of the reproductive - related pressure of the infertile women were negatively correlated with the endometrium and the FI in the endometrium ( r = - 0.304 , P0.001 ; r = - 0.407 , P0.001 ) . Conclusion 1 . There is no difference in the endometrial thickness , type , volume and the thickness of VI and VFI in the endometrium and the endometrium , and there is a negative correlation between the reproductive pressure of the infertile women and the FI in the endometrium and the endometrium , which is not related to other indices of blood flow .
【学位授予单位】：郑州大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R473.71

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