基于CBCT的三维重建技术在原发性肝癌TACE治疗中的应用

发布时间：2018-06-01 03:56

本文选题：肝动脉栓塞化疗 + 锥形束CT　；参考：《基因组学与应用生物学》2017年09期

【摘要】：为了深入了解基于CBCT的三维重建技术在原发性肝癌TACE治疗中的应用,本研究对在我院进行TACE治疗的原发性肝癌患者,分别采用基于CBCT的三维重建技术和常规的DSA技术进行分析比较。我们选取我院2013年1月~2015年10月确诊的67例原发性肝癌患者,采用随机数字表法分为CBCT组34例、血管造影(DAS组)33例,两组均采用TACE治疗,术中分别给予CBCT及三维重建、DSA技术进行手术指指导。研究表明:CBCT组对肿瘤供血动脉检出正确率、超选择动脉插管成功率、碘油在病灶中完全沉积率均高于DSA组(p0.05);CBCT组的手术时间、辐射总剂量均高于DSA组(p0.05);术后一个月复查,CBCT组CR 17.65%、PR 73.53%、SD 8.82%,DSA组CR 6.06%、PR 66.67%、SD 21.21%、PD 6.06%,两组比较差异具有统计学意义(p0.05);术后一个月复查,CBCT组血清AFP水平低于DSA组(p0.05);两组患者的KPS评分较本组术前均显著的提高(p0.05),两组间的KPS评分差异无统计学意义(p0.05)。我们的研究初步得出结论:基于CBCT的三维重建技术在原发性肝癌TACE治疗中较DSA技术能够更好的检出肿瘤的供血动脉、指导手术更加便捷和精确,能达到更好的手术效果。
[Abstract]:In order to understand the application of three-dimensional reconstruction technique based on CBCT in the treatment of primary liver cancer (HCC) with TACE, we studied the patients with primary liver cancer treated with TACE in our hospital. Three-dimensional reconstruction technology based on CBCT and conventional DSA technology are used to analyze and compare. From January 2013 to October 2015, 67 patients with primary liver cancer were randomly divided into CBCT group (n = 34) and angiography group (n = 33). Both groups were treated with TACE. CBCT and three-dimensional reconstruction were used to guide the operation. The results showed that the accuracy rate of detecting tumor supplying artery, the success rate of super selective artery intubation, the complete deposition rate of lipiodol in the lesion in the group of 10% CBCT were higher than those in the group of DSA (p 0.05). The total dose of radiation was higher than that of DSA group (P 0.05), and the level of serum AFP in CBCT group was lower than that in DSA group one month after operation. The serum AFP level in CBCT group was lower than that in DSA group (P 0.05). The scores were significantly higher than those before operation (P 0.05). There was no significant difference in KPS score between the two groups (P 0.05). Our preliminary conclusion is that 3D reconstruction based on CBCT can detect the blood supply artery of primary liver cancer better than that of DSA in TACE therapy. It is more convenient and accurate to guide the operation and can achieve better operation effect.
【作者单位】：河北医科大学第四医院放射科;
【基金】：河北医科大学第四医院资助
【分类号】：R730.44;R735.7

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