常规超声及ABVS对乳腺结节病理结果对照研究
发布时间:2018-06-09 02:58
本文选题:常规超声 + 自动乳腺容积扫描 ; 参考:《中国超声医学杂志》2017年10期
【摘要】:目的探讨常规超声(US)联合自动乳腺全容积扫描(ABVS)技术对乳腺结节分类诊断的价值。方法回顾性分析104例(125个结节)经过US和ABVS检查的乳腺结节患者。以病理结果为金标准,分析US、US联合ABVS对乳腺结节BI-RADS分类的灵敏度、特异度、准确率和诊断价值。结果 US对125个结节BI-RADS分类诊断的灵敏度、特异度、准确率分别为94.2%、75.3%、83.2%;US+ABVS对125个结节BI-RADS分类诊断的灵敏度、特异度、准确率分别为96.2%、86.3%、90.4%;ROC曲线分析US、US联合ABVS对乳腺结节BI-RADS分类的曲线下面积(AUC)分别为0.948、0.979;分析US、US+ABVS对乳腺恶性结节BI-RADS分类与人乳腺球蛋白(hMAM)表达水平间存在正相关(r=0.573,P=0.000;r=0.645,P=0.000)。结论 US、US联合ABVS技术对乳腺结节具有较高的诊断价值,US、US联合ABVS对乳腺恶性结节BI-RADS分类与hMAM呈正相关,因此其可在一定程度上反映乳腺癌细胞的增殖性和侵袭力。
[Abstract]:Objective to evaluate the diagnostic value of conventional ultrasound (USS) combined with automatic full volume mammary gland scanning (ABVS) in the classification of breast nodules. Methods 104 patients (125 nodules) underwent US and ABVS examination were retrospectively analyzed. The sensitivity, specificity, accuracy and diagnostic value of USUS combined with ABVS in classification of breast nodule BI-RADS were analyzed. Results the sensitivity, specificity and accuracy of US in the diagnosis of 125 nodules by BI-RADS were 94.2and 75.3and 83.2respectively. The area under the curve of USUS combined with ABVS for classification of breast nodule BI-RADS was 0.948 卤0.979, respectively. There was a positive correlation between USUS ABVS classification of malignant breast nodules BI-RADS and the expression level of human mammary globulin hMAM. There was a positive correlation between USUS ABVS and the expression level of human mammary globulin hMAM. Conclusion USUS combined with ABVS has a high diagnostic value for breast nodules. The classification of BI-RADS in malignant nodules of breast is positively correlated with HMAM, so it can reflect the proliferation and invasiveness of breast cancer cells to some extent.
【作者单位】: 兰州大学第一医院超声科;
【基金】:甘肃省自然科学基金(No.1606RJZA118)
【分类号】:R445.1;R737.9
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