拟输血患者血型不规则抗体检测结果的回顾性分析

发布时间：2018-06-19 04:27

本文选题：血型不规则抗体 + 输血　；参考：《细胞与分子免疫学杂志》2017年09期

【摘要】：目的探讨拟输血患者血型不规则抗体的检出及分布情况,以指导临床合理安全用血。方法应用盐水法、抗人球蛋白法和微柱凝胶技术对58 565例拟输血住院及急诊患者进行血型不规则抗体检测,对阳性结果进一步采用谱细胞进行抗体特异性鉴定。结果共检出不规则抗体阳性351例,检出率为0.60%(351/58 565)。鉴定出特异性抗体282例,检出率为0.48%(282/58 565);自身抗体36例,检出率为0.06%(36/58 565);无法鉴定抗体特异性共33例,占0.06%(33/58 565)。不同性别患者不规则抗体的检出率比较:女性患者222例,阳性率为0.73%(222/30 582)显著高于男性患者129例,阳性率为0.46%(129/27 983)。结论拟输血患者有必要进行不规则抗体筛查和特异性鉴定,避免免疫性输血反应的发生。
[Abstract]:Objective to explore the detection and distribution of irregular antibody of blood group in patients with blood transfusion in order to guide the rational and safe use of blood. Method of saline, anti human globulin and microcolumn gel technique were used to detect irregular antibody of blood group in 58565 cases of hospitalized and emergency patients, and the positive results were further used to carry out antibody specific cells. Results 351 cases of irregular antibody positive were detected, the detection rate was 0.60% (351/58 565). The specific antibody was identified in 282 cases, the detection rate was 0.48% (282/58 565); 36 cases of autoantibodies were 0.06% (36/58 565); 33 cases of antibody specificity were not identified, 0.06% (33/58 565). The detection rate of irregular antibodies in different sex patients was compared. Comparison: 222 cases of female patients, the positive rate was 0.73% (222/30 582) significantly higher than the male patients 129 cases, the positive rate was 0.46% (129/27 983). Conclusion the patients for the blood transfusion are necessary to carry out irregular antibody screening and specific identification, to avoid the occurrence of immune transfusion reaction.
【作者单位】：第四军医大学唐都医院输血科;
【基金】：陕西省自然科学基金(2009JM4006) 陕西省社发公关项目(2010K15-03-07)
【分类号】：R446.6;R457.1

【相似文献】