实验兔皮内、皮下注射钆双胺行间质MR淋巴管成像对脊柱旁淋巴干显像的对比分析

发布时间：2018-06-20 17:46

本文选题：磁共振成像 + 淋巴管造影术　；参考：《中国医学影像技术》2017年08期

【摘要】：目的探讨经兔足背皮内、皮下注射钆双胺行脊柱旁淋巴干MR成像的可行性。方法选取新西兰大白兔8只,首先经足背皮内注射钆双铵(皮内组),间隔3天后再经皮下注射(皮下组),采集冠状位三维扰相梯度回波序列(fl3dcor)图像,分别评价腰淋巴干及胸导管的显示情况。结果皮内组显示所有兔两侧乆窝淋巴结、髂淋巴结及主动脉下淋巴结明显强化,强化持续时间大于30min,最长达90min;6例腰淋巴干全程及乳糜池明显强化;5例可见部分胸导管强化。皮下组显示所有兔两侧乆窝淋巴结均明显强化,但腰淋巴结、腰淋巴干及胸导管未见强化。腰淋巴干及胸导管强化程度总评分皮内组与皮下组差异有统计学意义(t=100.00,P=0.0002)。结论足背皮内注射钆双胺淋巴管成像能较皮下注射更好地显示腰干淋巴管。
[Abstract]:Objective to investigate the feasibility of subcutaneous injection of gadolinium diamine in paraspinal lymphoid trunk Mr imaging. Methods eight New Zealand white rabbits were selected. First, gadolinium bisammonium was injected into the dorsum of foot (intradermal group), then subcutaneously injected (subcutaneous group) after 3 days interval. The coronal 3D scrambling phase gradient echo sequence fl3dcorwas collected. To evaluate the display of lumbar lymphatic trunk and thoracic duct respectively. Results in the intradermal group, the bilateral flanking lymph nodes, iliac lymph nodes and subaortic lymph nodes were obviously enhanced, and the enhancement lasted longer than 30 min. The longest time was 90 min in 6 cases of lumbar lymphoid trunk and chylous cistern, and 5 cases showed partial enhancement of thoracic ducts. In the subcutaneous group, all the flanking lymph nodes were obviously enhanced, but the lumbar lymph nodes, trunk of lumbar lymph nodes and thoracic ducts were not enhanced. Total score of Lumbar lymphoid Trunk and Thoracic Catheter Enhancement degree the difference between the intradermal group and the subcutaneous group was statistically significant. Conclusion Intradermal injection of gadolinium diamine lymphatic vessel imaging can better display lumbar lymphatic vessels than subcutaneous injection.
【作者单位】：浙江大学医学院附属儿童医院放射科;杭州市儿童医院放射科;湖州市妇幼保健院放射科;
【基金】：2014年浙江省医药卫生科技计划项目(2014KYA121)
【分类号】：R445.2

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