血栓弹力图在创伤性凝血病中的应用
发布时间:2018-07-10 08:22
本文选题:血栓弹力图 + 创伤性凝血病 ; 参考:《生物医学工程与临床》2017年03期
【摘要】:创伤导致约30%患者在入院时已并发凝血功能障碍。凝血功能障碍筛选试验在严重创伤出血患者中很难预测出血倾向,而血栓弹力图(TEG)可以显示从血凝块开始形成到溶解时所有阶段的变化。其优势是可快速识别纤溶亢进。文章就TEG工作原理、优缺点及其在创伤性凝血病患者中临床应用进行阐述。TEG在创伤患者中的应用有助于早期预测输血、指导大量输血复苏、有助于评估创伤患者预后、联合血小板图鉴别诊断创伤前是否应用抗血小板药物造成的血小板功能的下降、区分机械性出血、加强重组活性凝血因子Ⅶ(rFⅦa)的管理,同时也对是否、何时使用抗纤溶药物等提供依据。
[Abstract]:Trauma resulted in about 30% of patients with coagulation dysfunction at admission. Screening tests for coagulation dysfunction are difficult to predict bleeding tendency in patients with severe traumatic hemorrhage, while thromboelastography (TEG) can show changes in all stages from the beginning of clot formation to dissolution. Its advantage is that it can quickly identify hyperfibrinolysis. In this paper, the working principle, advantages and disadvantages of TEG and its clinical application in patients with traumatic coagulation disease are discussed. The application of TEG in trauma patients is helpful for early prediction of blood transfusion, guidance of blood transfusion resuscitation and evaluation of prognosis of trauma patients. In combination with thrombography, the differential diagnosis of platelet dysfunction caused by antiplatelet drugs before trauma, the differentiation of mechanical hemorrhage, the enhancement of the management of recombinant active coagulation factor 鈪,
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