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重庆地区婴幼儿和儿童血凝五项参考区间的调查

发布时间:2018-08-04 11:13
【摘要】:目的建立重庆地区婴幼儿和儿童血凝检查项目的参考区间,以更好地服务于临床。方法采用Sysmex CS5100、Sysmex CSA2000全自动血凝分析仪检测重庆地区经健康筛查的5 119例儿童的凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、血浆纤维蛋白原(FIB)、凝血酶时间(TT)、血浆D-二聚体(D-D)血凝五项。将所有儿童根据年龄分为6组:新生儿(0~15d)、新生儿(15d至小于1个月)、婴儿(1~7个月)、幼儿(7个月至小于3岁)、儿童(3~7岁)、儿童(7~15岁)组,进行比较分析。正态分布的资料按照喁±1.96s确定参考区间,偏态分布的资料按照P_(2.5)~P_(97.5)确定参考区间。结果本室血凝五项参考区间,PT:11.1~20.2s(0~15d)、10.7~15.8s(15d至小于1个月)、9.9~13.5s(1个月至15岁);APTT:28.8~91.6s(0~15d)、33.3~64.2s(15d至小于1个月)、24.0~53.2s(1~7个月)、21.2~39.2s(7个月至15岁);FIB:1.45~3.52g/L(0~3岁)、1.50~3.52g/L(3~15岁);TT:15.4~26.3s(0~15d)、14.9~21.4s(15d至小于7个月)、14.7~20.1s(7个月至小于3岁)、14.9~19.3s(3~15岁);D-D:0.1~5.1mg/L(0~15d)、0.2~2.2mg/L(15d至小于1个月)、0.1~1.1mg/L(1~7个月)、0.1~1.4 mg/L(7个月至小于3岁)、0.1~1.3 mg/L(3~7岁)、0~1.0 mg/L(7~15岁)。结论初步建立了重庆地区婴幼儿和儿童血凝五项(PT、APTT、FIB、TT、D-D)的参考区间,为该地区婴幼儿及儿童相关疾病的诊疗提供了更准确的依据。
[Abstract]:Objective to establish the reference range of hemagglutination examination for infants and children in Chongqing. Methods the prothrombin time (PT),) activated partial thromboplastin time (APTT), plasma fibrinogen (FIB), thrombin time (TT), plasma D-dimer (D-D) hemagglutination were measured by Sysmex CS5100 Sysmex CSA2000 automatic hemagglutination analyzer. All the children were divided into 6 groups according to their age: newborns (0 ~ 15 days), newborns (15 days to less than 1 month), infants (1 ~ 7 months), infants (7 months to less than 3 years old), children (3 ~ 7 years old) and children (7 ~ 15 years old). The reference interval is determined according to the data of normal distribution and P _ (2.5) / P _ (97.5), and the reference interval is determined according to the data of normal distribution 卤1.96 s and the data of skew distribution according to P _ (2.5) / P _ (97.5). 缁撴灉鏈琛,

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