甲状旁腺切除对血液透析患者颈-股动脉脉搏波速度的影响

发布时间：2018-08-27 11:17

【摘要】：目的:探讨甲状旁腺切除对血液透析患者颈-股动脉脉搏波速度(cfPWV)的影响。方法:选取规范药物治疗无效行甲状旁腺全切(tPTX)的重度继发性甲旁亢患者35例作为治疗组,选取健康志愿者30例作为对照组。治疗组术前与术后1年分别检测肝肾功能、血常规、全段甲状旁腺激素(iPTH)、cfPWV,对照组测量cfPWV。比较术前与术后1年患者临床及实验室指标、cfPWV变化;治疗组1年后cfPWV与对照组进行比较。结果:术后1年患者iPTH、血清钙、血清磷较术前显著下降,差异有统计学意义(P0.01);术后1年患者血红蛋白、血浆白蛋白水平较术前显著升高,差异有统计学意义(P0.01);术后1年患者cf PWV较术前显著下降,差异有统计学意义(P0.01);治疗组患者术后1年cf PWV显著高于对照组,差异有统计学意义(P0.01)。结论:t PTX可降低血液透析患者cfPWV。
[Abstract]:Objective: to investigate the effect of parathyroidectomy on carotid artery pulse wave velocity (cfPWV) in hemodialysis patients. Methods: 35 patients with severe secondary hyperthyroidism who had no effect on parathyroid gland resection (tPTX) were selected as treatment group and 30 healthy volunteers as control group. The liver and kidney function, blood routine, whole parathyroid hormone (iPTH) and cfPWV were measured before and 1 year after operation in the treatment group and cfPWV. in the control group. The clinical and laboratory indexes were compared between preoperative and postoperative year, and the cfPWV of the treatment group was compared with that of the control group after 1 year. Results: the levels of serum calcium and phosphorus in iPTH, patients were significantly lower than those before operation (P0.01), the levels of hemoglobin and plasma albumin were significantly higher than those before operation (P0.01). The difference was statistically significant (P0.01); the cf PWV of the patients after 1 year was significantly lower than that of the pre-operation (P0.01); the cf PWV of the treatment group was significantly higher than that of the control group (P0.01) one year after operation, the difference was statistically significant (P0.01). Conclusion the cfPWV. of hemodialysis patients can be decreased by PTX.
【作者单位】：扬州大学临床医学院肾内科;扬州大学临床医学院心功能科;
【基金】：江苏省苏北人民医院院基金(编号:yzucms201634)
【分类号】：R653;R692.5

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