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浙江沿海地区无偿献血人群HTLV感染的流行病学与知晓情况调查

发布时间:2018-11-14 10:05
【摘要】:目的了解浙江沿海地区无偿献血者人类嗜T淋巴细胞病毒(HTLV)感染状况,提出综合性防控策略。方法采用ELISA方法筛查2013-2015年浙江省沿海6市(区)无偿献血者58 609(人)份血清中抗-HTLV-Ⅰ/Ⅱ,阳性者以WB法确证,并做HTLV基因测序和同源性分析;随机对10 197名献血者开展HTLV知晓情况问卷调查。结果本组献血者人群的抗-HTLV阳性率0.01%(5/58 609),抗体类型为抗-HTLV-Ⅰ,均属世界群世界人种亚型;该5位HTLV感染者均为本地首次献血者,其中台州市发现的HTLV毒株与福建泉州的分离株同源,舟山市发现的HTLV毒株与日本的分离株MT-2同源。献血者对HTLV的知晓情况:随机问卷调查(10分制)人均得分0.75(0-8)分,其中1分者占调查对象的79.0%(8059/10 197),5分者占1.40%(143/10 197)。结论浙江沿海台州和舟山地区献血人群中存在HTLV感染和散在的小流行;献血者对HTLV的知识极其匮乏,亟待采取相应防控策略。
[Abstract]:Objective to investigate the status of human T lymphocyte virus (HTLV) infection among blood donors in coastal areas of Zhejiang province and to put forward comprehensive prevention and control strategies. Methods ELISA method was used to screen 58 609 (human) samples of free blood donors from 6 coastal cities (districts) of Zhejiang Province from 2013 to 2015. The positive individuals were confirmed by WB method, and HTLV gene sequencing and homology analysis were performed. A questionnaire survey was conducted among 10 197 blood donors on HTLV knowledge. Results the positive rate of anti-HTLV was 0. 01% (5 / 58,609) in this group of blood donors. The antibody type was anti-HTLV- 鈪,

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