药物滥用人群传染病的疾病负担评估

发布时间：2018-11-16 21:35

【摘要】：目的了解我国吸毒人群传染性疾病的患病风险、期望寿命、治疗费用和吸毒费用,评估药物滥用人群中感染三大传染疾病的负担。方法以期望寿命年、疾病患病率、疾病治疗费用和吸毒费用为评价指标,利用马尔科夫状态转移决策模型以及成本效益模型评估吸毒人群疾病负担。结果吸毒人员平均期望寿命为13.66年;药物滥用使用第1年,丙型肝炎、艾滋病和结核病的感染率分别为50.4%、3.3%和2.7%;3年后,药物滥用人群的累计病死率为26.35%,3种传染病的感染率达到最大值,各种感染率分别为59.78%、3.71%、3.11%;20年后,药物滥用人群的累计病死率达42.95%,各传染病的感染率分别为48.28%、2.02%、2.05%;一名药物滥用人员传染性疾病每年的总费用大约为2.98万元,其中治疗费用和毒资分别是2 495.79元和27 318.8元。结论药物滥用人群传染性疾病发病风险较高,治疗疾病的成本高。
[Abstract]:Objective to investigate the risk, life expectancy, treatment cost and drug use cost of infectious diseases among drug abusers in China, and to evaluate the burden of infection with three major infectious diseases in drug abusers. Methods the disease burden of drug users was evaluated by Markov state transition decision model and cost-benefit model, based on life expectancy years, disease prevalence rate, disease treatment cost and drug use cost. Results the average life expectancy of drug addicts was 13.66 years. In the first year of drug abuse, the infection rates of hepatitis C, AIDS and tuberculosis were 50.4% and 2.7%, respectively. Three years later, the cumulative mortality of drug abusers was 26.355.The infection rate of three infectious diseases reached the maximum, and the infection rates were 59.783.71and 3.11 respectively. 20 years later, the cumulative mortality of drug abusers was 42.95, and the infection rate of each infectious disease was 48.28 and 2.05 respectively. The total cost of infectious diseases of a drug abuser is about 29800 yuan per year, of which the cost of treatment and the cost of poison are 2 495.79 yuan and 27 318.8 yuan respectively. Conclusion the risk of infectious diseases in drug abusers is high and the cost of treatment is high.
【作者单位】：北京大学公共卫生学院;北京大学中国药物依赖性研究所;烟台大学数学与信息科学学院;北卡罗来纳大学教堂山分校公共卫生学院;加利福尼亚大学应用数学系;北京大学工学院生物医学工程系;
【基金】：国家自然科学基金资助项目(9154620017) 国家自然科学面上基金资助项目(6157010413)
【分类号】：R749.64

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