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深圳孕妇定植B族链球菌的分子分型研究

发布时间:2018-12-14 01:30
【摘要】:目的掌握深圳市孕妇定植B族链球菌(GBS)携带情况,并分析菌株的分子型别特征。方法对1 277名研究对象进行阴道拭子采样,对分离到的GBS菌株进行血清分型和MLST分型检测,采用对应分析探究分子型别间关联性。结果孕妇GBS携带率为4.5%。ST19/Ⅲ(24.6%)和ST17/Ⅲ(17.5%)是本研究主要流行的GBS菌株;对应分析结果提示菌株血清分型和MLST分型之间存在关联(X~2=81.43,P0.001),其中ST17、ST19、ST27、ST651、ST862和Ⅲ型相关;ST12和Ⅴ型相关;ST10和Ⅰb型相关;ST103、ST485、ST624和Ⅰa型相关。结论孕妇GBS主要流行ST19/Ⅲ和ST17/Ⅲ,菌株分子型别存在关联性。
[Abstract]:Objective to study the (GBS) carriers of group B streptococcus in pregnant women in Shenzhen and to analyze the molecular characteristics of the strains. Methods the vaginal swabs were collected from 1 277 subjects. Serotyping and MLST typing were performed on the isolated GBS strains. The correlation between molecular types was explored by correspondence analysis. Results 4.5%.ST19/ 鈪,

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