血液循环泵治疗的脊髓损伤患者发生下肢血栓的影响因素

发布时间：2019-01-17 12:39

【摘要】：目的探讨脊髓损伤(spinal cord injury,SCI)且应用血液循环泵治疗的患者下肢血栓的发生现状及影响因素,为临床有效的防治脊髓损伤患者下肢血栓提供依据。方法本研究采用病例对照研究方法。选取2015年9月至2016年8月期间在唐山市第二医院住院的所有脊髓损伤并接受血液循环泵治疗的患者422例为对象,在患者入院3天内完成基线调查,调查患者的一般人口学资料,并完成下肢静脉血栓认知调查问卷和下肢静脉血栓健康信念调查问卷;在患者出院时通过查阅病例调查患者的治疗及手术情况、临床症状等情况,并调查患者在经血液循环泵治疗期间发生下肢静脉血栓的情况并记录发生时间,以发生下肢血栓的脊髓损伤患者作为病例组,未发生下肢血栓的脊髓损伤患者作为对照组,统计分析经血液循环泵治疗的脊髓损伤患者发生下肢血栓的影响因素。数据采用SPSS17.0统计软件进行分析,采用单因素、多因素logistic回归模型分析。结果1本次调查的422例脊髓损伤患者中,发生下肢血栓的患者共68例,发生率16.1%。2脊髓损伤患者下肢血栓发生的影响因素单因素分析结果:病例组与对照组患者在婚姻、文化程度、睡眠、损伤程度、排尿情况、脉搏、低分子肝素的注射、血液循环泵的使用、输血史、DVT的认知及健康信念水平等方面差异有统计学意义(P0.05)。3脊髓损伤患者下肢静脉血栓发生的影响因素logistic多因素回归分析结果:患者的损伤程度(OR=2.105,P0.05)、排尿(OR=3.313,P0.05)、文化程度(OR=0.560,P0.05)、低分子肝素的注射(OR=0.290,P0.05)、血液循环泵的使用(OR=0.499,P0.05)、下肢静脉血栓的认知水平(OR=0.911,P0.05)是血液循环泵治疗的脊髓损伤患者下肢静脉血栓发生的影响因素。结论1接受血液循环泵治疗的住院脊髓损伤患者下肢血栓的发生率16.1%。2患者的损伤程度、排尿情况、文化程度、低分子肝素的注射、血液循环泵的使用、下肢静脉血栓的认知水平是血液循环泵治疗的脊髓损伤患者下肢静脉血栓发生的影响因素。
[Abstract]:Objective to investigate the status quo and influencing factors of lower extremity thrombosis in patients with spinal cord injury (spinal cord injury,SCI) treated with blood circulation pump, and to provide evidence for clinical prevention and treatment of lower extremity thrombosis in patients with spinal cord injury. Methods A case-control study was conducted. From September 2015 to August 2016, 422 patients with spinal cord injury who were hospitalized in the second Hospital of Tangshan City and received blood circulation pump therapy were selected as subjects. The baseline survey was completed within 3 days after admission, and the general demographic data of the patients were investigated. And completed the lower extremity venous thrombosis cognition questionnaire and the lower extremity venous thrombosis health belief questionnaire; At the time of discharge from hospital, the patients were investigated for treatment and operation, clinical symptoms and so on. The patients' venous thrombosis of lower extremity was investigated during the treatment of blood circulation pump and the time of occurrence was recorded. Patients with spinal cord injury (sci) with lower extremity thrombus as case group and patients with spinal cord injury (sci) without lower extremity thrombus as control group were used as control group. The influencing factors of lower extremity thrombosis in patients with spinal cord injury treated by blood circulation pump were analyzed statistically. The data were analyzed by SPSS17.0 statistical software, single factor and multi-factor logistic regression model. Results (1) of 422 patients with spinal cord injury, 68 had lower extremity thrombosis. The incidence of lower extremity thrombosis in patients with spinal cord injury was analyzed by univariate analysis. Results: marriage, education, sleep, injury, urination, pulse, injection of low molecular weight heparin (LMWH) were observed in the case group and the control group. Use of blood circulation pumps, history of blood transfusions, There were significant differences in the cognitive and health belief levels of DVT (P0.05). 3 logistic multivariate regression analysis showed that the degree of injury (OR=2.105,P0.05) in patients with spinal cord injury was related to the occurrence of venous thrombosis in lower extremity. Urination (OR=3.313,P0.05), education level (OR=0.560,P0.05), low molecular weight heparin injection (OR=0.290,P0.05), blood circulation pump use (OR=0.499,P0.05), The cognitive level (OR=0.911,P0.05) of venous thrombosis of lower extremity is the influencing factor of venous thrombosis of lower extremity in patients with spinal cord injury treated by blood circulation pump. Conclusion 1 the incidence of lower extremity thrombosis in patients with spinal cord injury treated by blood circulation pump is 16.1.2 the degree of injury, urination, education, injection of low molecular weight heparin, use of blood circulation pump. The cognitive level of venous thrombosis of lower extremity is the influencing factor of venous thrombosis in patients with spinal cord injury treated by blood circulation pump.
【学位授予单位】：华北理工大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R473.6

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